| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 12 | 12 | 2 | 6 | 4.19 | .331 | 1.44 | 9.2 | 3.9 | 9.3 | 81.2 | 83 | 40 | 38 | 14 | 35 | 84 | 1 | 0 | 0 | 0 | 7 | 3 | 1 | 4.58 |
| SP | Buchholz, C.Buchholz, Clay >> | 29 | 2013 | R | 82 | 12 | 12 | 2 | 8 | 7.10 | .342 | 1.53 | 10.1 | 3.8 | 7.6 | 64.2 | 72 | 51 | 51 | 12 | 27 | 54 | 0 | 0 | 0 | 0 | 3 | 2 | 3 | 5.11 |
| SP | Beckett, J.Beckett, Josh # >> | 31 | 2011 | R | 75 | 12 | 12 | 4 | 3 | 4.82 | .319 | 1.35 | 9.1 | 3.2 | 8.0 | 74.2 | 75 | 40 | 40 | 12 | 26 | 66 | 2 | 0 | 0 | 0 | 6 | 4 | 2 | 4.54 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 65 | 12 | 12 | 6 | 4 | 3.60 | .318 | 1.38 | 8.2 | 4.2 | 8.1 | 80.0 | 73 | 34 | 32 | 11 | 37 | 72 | 1 | 0 | 0 | 0 | 8 | 2 | 2 | 4.45 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 34 | 0 | 0 | 2 | 3.04 | .257 | 1.04 | 6.3 | 3.1 | 8.8 | 47.1 | 33 | 16 | 16 | 6 | 16 | 46 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 3.72 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 80 | 27 | 0 | 4 | 0 | 5.30 | .310 | 1.32 | 9.8 | 2.3 | 11.3 | 35.2 | 38 | 21 | 21 | 9 | 9 | 44 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 4.69 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 61 | 21 | 0 | 2 | 1 | 2.51 | .265 | 1.08 | 5.8 | 4.2 | 10.6 | 28.2 | 18 | 8 | 8 | 0 | 13 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.04 |
| RP | Rivero, F.Rivero, Felipe >> | 27 | 2019 | L | 44 | 20 | 0 | 2 | 0 | 6.10 | .380 | 1.84 | 12.6 | 4.5 | 11.7 | 20.2 | 28 | 14 | 14 | 6 | 10 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.80 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 33 | 16 | 0 | 2 | 0 | 4.08 | .293 | 1.25 | 7.4 | 4.2 | 11.1 | 17.2 | 14 | 8 | 8 | 1 | 8 | 21 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 2.71 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 49 | 2 | 0 | 0 | 0 | 0.00 | .143 | 0.50 | 4.5 | 0.0 | 18.0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |
| SP | Berrios, J.Berrios, Jose >> | 24 | 2018 | R | 35 | 11 | 0 | 1 | 1 | 5.71 | .307 | 1.21 | 7.4 | 3.7 | 12.2 | 17.1 | 14 | 11 | 11 | 5 | 7 | 23 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 5.71 |