| SP | Buehrle, M.Buehrle, Mark >> | 28 | 2001 | L | 92 | 26 | 26 | 10 | 6 | 3.29 | .259 | 1.02 | 7.8 | 1.3 | 6.8 | 202.2 | 176 | 82 | 74 | 27 | 30 | 153 | 4 | 0 | 0 | 1 | 17 | 7 | 2 | 3.77 |
| SP | McCarthy, B.McCarthy, Brandon >> | 24 | 2005 | R | 89 | 26 | 26 | 10 | 9 | 4.98 | .329 | 1.44 | 9.8 | 3.1 | 5.5 | 132.0 | 144 | 79 | 73 | 22 | 46 | 81 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 5.08 |
| SP | Garland, J.Garland, Jon # >> | 28 | 2002 | R | 69 | 21 | 17 | 6 | 7 | 5.18 | .338 | 1.49 | 9.3 | 4.1 | 5.4 | 113.0 | 117 | 66 | 65 | 16 | 51 | 68 | 0 | 0 | 0 | 0 | 6 | 5 | 7 | 5.12 |
| RP | Castillo, C.Castillo, Carlos >> | 32 | 1998 | R | 83 | 57 | 0 | 2 | 5 | 4.74 | .289 | 1.17 | 8.1 | 2.5 | 6.7 | 100.2 | 90 | 55 | 53 | 13 | 28 | 74 | 0 | 0 | 4 | 0 | 0 | 5 | 1 | 4.20 |
| RP | Marte, D.Marte, Damaso >> | 32 | 2002 | L | 82 | 43 | 0 | 4 | 2 | 4.24 | .320 | 1.35 | 7.8 | 4.4 | 8.3 | 51.0 | 44 | 24 | 24 | 9 | 25 | 47 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 5.10 |
| CL | Cotts, N.Cotts, Neal † >> | 27 | 2005 | L | 97 | 56 | 0 | 3 | 6 | 2.79 | .222 | 0.86 | 4.7 | 3.1 | 10.2 | 67.2 | 35 | 23 | 21 | 5 | 23 | 76 | 0 | 31 | 3 | 0 | 0 | 0 | 4 | 2.73 |