| SP | Lyon, B.Lyon, Brandon † >> | 26 | 2001 | R | 94 | 31 | 31 | 17 | 6 | 2.90 | .268 | 1.08 | 7.2 | 2.6 | 6.6 | 217.1 | 173 | 77 | 70 | 21 | 62 | 160 | 3 | 0 | 0 | 1 | 23 | 4 | 0 | 3.70 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2001 | R | 96 | 33 | 33 | 17 | 8 | 3.40 | .275 | 1.13 | 7.9 | 2.3 | 7.5 | 243.1 | 212 | 93 | 92 | 28 | 62 | 203 | 6 | 0 | 0 | 2 | 18 | 3 | 4 | 3.63 |
| SP | Escobar, K.Escobar, Kelvim >> | 29 | 1998 | R | 99 | 26 | 26 | 11 | 7 | 3.63 | .295 | 1.25 | 8.9 | 2.4 | 6.6 | 143.2 | 142 | 60 | 58 | 13 | 38 | 105 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 3.51 |
| SP | Clemens, R.Clemens, Roger # >> | 43 | 2005 | R | 95 | 30 | 30 | 12 | 14 | 4.75 | .303 | 1.26 | 8.1 | 3.3 | 7.5 | 191.1 | 171 | 105 | 101 | 30 | 71 | 160 | 1 | 0 | 0 | 0 | 14 | 8 | 0 | 4.61 |
| SP | Carpenter, C.Carpenter, Chris >> | 30 | 2005 | R | 86 | 24 | 24 | 9 | 12 | 4.63 | .295 | 1.20 | 8.8 | 2.1 | 6.2 | 149.2 | 146 | 77 | 77 | 21 | 34 | 103 | 4 | 0 | 0 | 2 | 14 | 8 | 2 | 4.30 |
| RP | Rhodes, A.Rhodes, Arthur # >> | 36 | 2005 | L | 85 | 32 | 32 | 7 | 14 | 5.13 | .325 | 1.40 | 9.5 | 3.2 | 6.6 | 189.1 | 199 | 121 | 108 | 23 | 67 | 138 | 1 | 0 | 0 | 0 | 15 | 7 | 6 | 4.30 |
| RP | Thurman, C.Thurman, Corey >> | 27 | 2002 | R | 76 | 25 | 0 | 1 | 0 | 1.40 | .232 | 0.88 | 5.7 | 2.4 | 9.2 | 38.2 | 24 | 6 | 6 | 1 | 10 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2.16 |
| SU | Kershner, J.Kershner, Jason >> | 29 | 2003 | L | 84 | 38 | 0 | 2 | 2 | 3.22 | .260 | 1.03 | 7.0 | 2.5 | 5.7 | 44.2 | 34 | 16 | 16 | 2 | 12 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.20 |
| SP | Hunter, R.Hunter, Rich >> | 31 | 1996 | R | 85 | 11 | 2 | 2 | 2 | 5.18 | .305 | 1.32 | 9.9 | 2.1 | 6.2 | 48.2 | 53 | 28 | 28 | 9 | 11 | 33 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.75 |
| CL | Walker, K.Walker, Kevin † >> | 29 | 2000 | L | 97 | 57 | 0 | 7 | 4 | 2.63 | .257 | 1.02 | 6.2 | 3.0 | 8.9 | 68.1 | 47 | 20 | 20 | 9 | 23 | 67 | 0 | 39 | 4 | 0 | 0 | 1 | 1 | 3.81 |