| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 34 | 34 | 25 | 6 | 2.78 | .273 | 1.10 | 7.8 | 2.1 | 5.4 | 252.1 | 218 | 87 | 78 | 16 | 60 | 151 | 13 | 0 | 0 | 6 | 23 | 6 | 4 | 3.41 |
| SP | Alexander, P.Alexander, Pete # >> | 28 | 1915 | R | 88 | 34 | 34 | 16 | 13 | 4.68 | .294 | 1.23 | 9.0 | 2.1 | 5.0 | 217.1 | 218 | 120 | 113 | 25 | 50 | 120 | 8 | 0 | 0 | 2 | 16 | 4 | 2 | 4.14 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 32 | 32 | 6 | 13 | 5.23 | .337 | 1.50 | 10.1 | 3.4 | 7.4 | 175.2 | 196 | 117 | 102 | 26 | 67 | 144 | 1 | 0 | 0 | 0 | 15 | 5 | 6 | 4.52 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 32 | 32 | 13 | 6 | 5.27 | .329 | 1.44 | 8.9 | 4.0 | 8.0 | 172.1 | 171 | 104 | 101 | 25 | 77 | 153 | 0 | 0 | 0 | 0 | 13 | 5 | 2 | 4.54 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 86 | 0 | 6 | 2 | 4.80 | .300 | 1.26 | 8.6 | 2.8 | 7.3 | 86.1 | 82 | 46 | 46 | 9 | 27 | 70 | 0 | 6 | 3 | 0 | 0 | 2 | 13 | 3.74 |
| RP | Brewer, J.Brewer, Jim † >> | 35 | 1972 | L | 73 | 84 | 0 | 8 | 5 | 3.58 | .292 | 1.24 | 7.0 | 4.2 | 4.0 | 93.0 | 72 | 37 | 37 | 9 | 43 | 41 | 0 | 8 | 2 | 0 | 0 | 0 | 3 | 4.76 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 84 | 0 | 4 | 0 | 1.04 | .268 | 1.08 | 5.2 | 4.6 | 9.8 | 86.2 | 50 | 12 | 10 | 4 | 44 | 94 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 2.99 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 77 | 0 | 1 | 4 | 4.48 | .314 | 1.38 | 6.6 | 5.8 | 8.9 | 68.1 | 50 | 34 | 34 | 7 | 44 | 67 | 0 | 9 | 4 | 0 | 0 | 0 | 6 | 4.31 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 49 | 0 | 3 | 1 | 2.33 | .247 | 0.98 | 5.7 | 3.2 | 3.7 | 54.0 | 34 | 16 | 14 | 4 | 19 | 22 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 49 | 0 | 4 | 2 | 3.70 | .352 | 1.62 | 8.4 | 6.2 | 5.6 | 80.1 | 75 | 40 | 33 | 10 | 55 | 50 | 0 | 6 | 1 | 0 | 0 | 1 | 1 | 5.48 |