| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 17 | 17 | 7 | 6 | 4.05 | .309 | 1.31 | 9.2 | 2.7 | 7.9 | 104.1 | 106 | 49 | 47 | 11 | 31 | 91 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 3.61 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 17 | 17 | 13 | 1 | 1.45 | .252 | 0.97 | 5.1 | 3.6 | 6.5 | 124.0 | 70 | 22 | 20 | 7 | 50 | 90 | 0 | 0 | 0 | 0 | 16 | 5 | 2 | 3.61 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 16 | 16 | 10 | 1 | 4.12 | .303 | 1.25 | 7.6 | 3.7 | 5.0 | 98.1 | 83 | 49 | 45 | 6 | 40 | 54 | 2 | 0 | 0 | 1 | 8 | 5 | 2 | 4.07 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 44 | 0 | 1 | 2 | 2.30 | .237 | 0.93 | 5.7 | 2.7 | 10.0 | 43.0 | 27 | 13 | 11 | 4 | 13 | 48 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 2.88 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 34 | 0 | 1 | 2 | 5.55 | .298 | 1.23 | 9.8 | 1.5 | 6.4 | 24.1 | 26 | 16 | 15 | 6 | 4 | 17 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.46 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 37 | 0 | 1 | 1 | 1.35 | .184 | 0.68 | 3.5 | 2.8 | 7.3 | 26.2 | 10 | 4 | 4 | 1 | 8 | 21 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 2.81 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 25 | 0 | 1 | 5 | 4.34 | .263 | 1.00 | 4.0 | 5.0 | 7.4 | 29.0 | 13 | 15 | 14 | 2 | 16 | 24 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 4.10 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 25 | 0 | 1 | 2 | 2.27 | .272 | 1.09 | 8.5 | 1.5 | 4.6 | 35.2 | 33 | 9 | 9 | 3 | 6 | 18 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 3.69 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 13 | 0 | 0 | 1 | 4.50 | .323 | 1.36 | 8.4 | 3.9 | 9.0 | 14.0 | 13 | 7 | 7 | 5 | 6 | 14 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 7.14 |