| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 17 | 17 | 12 | 3 | 2.98 | .269 | 1.06 | 7.1 | 2.5 | 5.7 | 129.2 | 102 | 44 | 43 | 13 | 36 | 81 | 5 | 0 | 0 | 1 | 13 | 5 | 3 | 4.01 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 16 | 16 | 4 | 5 | 6.33 | .340 | 1.54 | 9.6 | 4.3 | 6.4 | 102.1 | 109 | 74 | 72 | 14 | 49 | 73 | 3 | 0 | 0 | 1 | 4 | 0 | 4 | 4.79 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 46 | 0 | 2 | 1 | 4.14 | .312 | 1.34 | 9.7 | 2.5 | 9.2 | 54.1 | 58 | 26 | 25 | 2 | 15 | 55 | 0 | 7 | 4 | 0 | 0 | 1 | 2 | 2.33 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 39 | 0 | 5 | 3 | 5.32 | .340 | 1.50 | 8.2 | 5.3 | 7.0 | 44.0 | 40 | 28 | 26 | 8 | 26 | 34 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 5.73 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 27 | 0 | 2 | 3 | 5.40 | .344 | 1.54 | 8.2 | 5.7 | 8.5 | 35.0 | 32 | 22 | 21 | 3 | 22 | 33 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.20 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 24 | 0 | 0 | 3 | 3.10 | .275 | 1.10 | 7.4 | 2.5 | 8.1 | 29.0 | 24 | 10 | 10 | 4 | 8 | 26 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.93 |