| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 8 | 8 | 2 | 5 | 5.40 | .361 | 1.66 | 10.7 | 4.3 | 9.2 | 48.1 | 57 | 30 | 29 | 7 | 23 | 49 | 0 | 0 | 0 | 0 | 4 | 2 | 5 | 4.42 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 8 | 8 | 1 | 5 | 5.28 | .310 | 1.33 | 9.5 | 2.5 | 8.1 | 58.0 | 61 | 34 | 34 | 12 | 16 | 52 | 2 | 0 | 0 | 0 | 2 | 1 | 2 | 4.78 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 7 | 7 | 3 | 2 | 4.30 | .313 | 1.32 | 7.6 | 4.3 | 4.1 | 44.0 | 37 | 21 | 21 | 5 | 21 | 20 | 1 | 0 | 0 | 0 | 4 | 2 | 4 | 5.14 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 22 | 0 | 1 | 2 | 5.74 | .304 | 1.31 | 10.4 | 1.7 | 8.3 | 26.2 | 30 | 17 | 17 | 5 | 5 | 24 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.23 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 20 | 0 | 2 | 1 | 5.40 | .343 | 1.57 | 10.3 | 4.3 | 6.0 | 21.2 | 24 | 15 | 13 | 3 | 10 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.95 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 11 | 0 | 2 | 1 | 1.64 | .267 | 1.05 | 5.3 | 4.1 | 4.1 | 22.0 | 13 | 4 | 4 | 0 | 10 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.59 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 1 | 1 | 0 | 0 | 7.11 | .240 | 0.95 | 9.0 | 0.0 | 6.0 | 6.1 | 6 | 5 | 5 | 3 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.17 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Vaughn, H.Vaughn, Hippo >> | 30 | 1918 | L | 40 | 3 | 0 | 0 | 0 | 0.00 | .167 | 0.60 | 6.0 | 0.0 | 0.0 | 3.1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |