| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 21 | 21 | 6 | 12 | 3.94 | .302 | 1.28 | 8.2 | 3.4 | 8.9 | 134.2 | 122 | 61 | 59 | 13 | 51 | 132 | 1 | 0 | 0 | 0 | 13 | 2 | 1 | 3.48 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 20 | 20 | 7 | 9 | 4.84 | .339 | 1.52 | 9.1 | 4.6 | 4.0 | 124.2 | 126 | 69 | 67 | 9 | 64 | 55 | 2 | 0 | 0 | 0 | 12 | 2 | 4 | 4.65 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 20 | 20 | 6 | 9 | 5.24 | .310 | 1.33 | 8.5 | 3.6 | 7.5 | 123.2 | 116 | 75 | 72 | 18 | 49 | 103 | 2 | 0 | 0 | 1 | 9 | 2 | 2 | 4.47 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 20 | 20 | 8 | 5 | 5.18 | .324 | 1.41 | 10.1 | 2.7 | 4.0 | 114.2 | 128 | 69 | 66 | 16 | 34 | 51 | 2 | 0 | 0 | 2 | 8 | 3 | 0 | 4.90 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 17 | 17 | 8 | 5 | 5.98 | .376 | 1.78 | 11.1 | 4.9 | 5.1 | 93.1 | 115 | 62 | 62 | 14 | 51 | 53 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 5.56 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 57 | 0 | 3 | 2 | 2.00 | .245 | 0.98 | 6.2 | 2.6 | 10.1 | 94.1 | 65 | 22 | 21 | 10 | 27 | 105 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.01 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 49 | 0 | 4 | 3 | 3.48 | .243 | 0.95 | 7.3 | 1.3 | 7.8 | 67.1 | 54 | 26 | 26 | 8 | 10 | 58 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 3.31 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 34 | 0 | 2 | 1 | 2.31 | .286 | 1.14 | 6.3 | 4.1 | 8.8 | 50.2 | 35 | 15 | 13 | 6 | 23 | 49 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 4.16 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 5 | 2 | 0 | 2 | 11.88 | .444 | 2.40 | 16.9 | 5.6 | 9.0 | 8.1 | 15 | 11 | 11 | 4 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.38 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 15 | 1 | 3 | 2 | 5.54 | .331 | 1.46 | 8.3 | 4.8 | 4.8 | 39.0 | 36 | 25 | 24 | 6 | 21 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.62 |