| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 36 | 36 | 15 | 16 | 3.71 | .310 | 1.33 | 8.2 | 3.8 | 8.5 | 232.2 | 212 | 101 | 96 | 21 | 98 | 219 | 0 | 0 | 0 | 0 | 24 | 3 | 13 | 3.59 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 31 | 31 | 14 | 13 | 4.44 | .294 | 1.24 | 8.8 | 2.4 | 7.5 | 225.0 | 220 | 116 | 111 | 34 | 59 | 188 | 9 | 0 | 0 | 0 | 11 | 2 | 3 | 4.11 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 30 | 30 | 12 | 11 | 5.08 | .333 | 1.47 | 9.4 | 3.9 | 4.9 | 180.2 | 188 | 112 | 102 | 22 | 77 | 98 | 1 | 0 | 0 | 0 | 14 | 5 | 17 | 4.87 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 91 | 0 | 5 | 6 | 3.28 | .259 | 1.03 | 7.0 | 2.3 | 8.7 | 123.1 | 96 | 47 | 45 | 14 | 31 | 119 | 0 | 14 | 4 | 0 | 0 | 2 | 2 | 3.35 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 76 | 0 | 7 | 4 | 4.00 | .301 | 1.28 | 8.1 | 3.6 | 6.2 | 96.2 | 86 | 46 | 43 | 13 | 38 | 66 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 4.60 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 49 | 0 | 4 | 2 | 3.49 | .299 | 1.25 | 6.7 | 4.7 | 4.6 | 87.2 | 65 | 34 | 34 | 9 | 45 | 44 | 0 | 10 | 2 | 0 | 0 | 2 | 3 | 4.95 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 3 | 3 | 2 | 0 | 3.00 | .172 | 0.63 | 5.3 | 0.4 | 6.4 | 24.0 | 14 | 11 | 8 | 6 | 1 | 17 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 4.96 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Vaughn, H.Vaughn, Hippo >> | 30 | 1918 | L | 41 | 19 | 0 | 1 | 1 | 4.28 | .311 | 1.32 | 8.3 | 3.7 | 4.0 | 27.1 | 25 | 17 | 13 | 3 | 11 | 12 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.89 |