| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 20 | 20 | 7 | 9 | 3.73 | .291 | 1.20 | 8.2 | 2.7 | 9.2 | 156.2 | 142 | 73 | 65 | 17 | 46 | 159 | 7 | 0 | 0 | 2 | 11 | 5 | 1 | 3.36 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 19 | 19 | 4 | 11 | 4.02 | .286 | 1.20 | 8.1 | 2.7 | 5.1 | 154.2 | 139 | 75 | 69 | 16 | 46 | 87 | 9 | 0 | 0 | 1 | 9 | 1 | 0 | 4.14 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 19 | 19 | 7 | 8 | 5.57 | .337 | 1.50 | 9.1 | 4.4 | 7.4 | 116.1 | 117 | 79 | 72 | 21 | 57 | 96 | 1 | 0 | 0 | 0 | 8 | 3 | 1 | 5.25 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 18 | 18 | 5 | 8 | 5.75 | .350 | 1.56 | 10.2 | 4.0 | 5.7 | 101.2 | 114 | 65 | 65 | 15 | 45 | 64 | 0 | 0 | 0 | 0 | 7 | 5 | 3 | 5.15 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 45 | 0 | 4 | 0 | 2.91 | .335 | 1.47 | 6.2 | 7.2 | 8.2 | 55.2 | 38 | 25 | 18 | 1 | 44 | 50 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 3.93 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 48 | 0 | 1 | 5 | 4.35 | .302 | 1.30 | 7.5 | 4.2 | 7.1 | 60.0 | 50 | 30 | 29 | 10 | 28 | 47 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 34 | 0 | 2 | 2 | 4.91 | .333 | 1.47 | 9.3 | 4.3 | 9.5 | 36.2 | 37 | 21 | 20 | 5 | 17 | 38 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.19 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 32 | 0 | 6 | 3 | 2.84 | .318 | 1.36 | 6.8 | 5.6 | 4.0 | 50.2 | 38 | 16 | 16 | 3 | 31 | 22 | 0 | 4 | 1 | 0 | 0 | 2 | 2 | 4.88 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 19 | 0 | 0 | 1 | 4.09 | .313 | 1.36 | 10.6 | 1.6 | 5.7 | 22.0 | 26 | 11 | 10 | 2 | 4 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.45 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 6 | 0 | 1 | 0 | 6.30 | .375 | 1.80 | 11.7 | 4.5 | 9.0 | 10.0 | 13 | 8 | 7 | 1 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.80 |