| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 9 | 12 | 5.00 | .299 | 1.25 | 8.4 | 2.9 | 8.7 | 210.2 | 197 | 122 | 117 | 22 | 67 | 203 | 2 | 0 | 0 | 2 | 17 | 6 | 3 | 3.47 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 33 | 33 | 8 | 14 | 4.24 | .316 | 1.37 | 9.3 | 3.0 | 8.8 | 222.2 | 230 | 116 | 105 | 34 | 74 | 218 | 3 | 0 | 0 | 1 | 20 | 4 | 1 | 4.08 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 16 | 13 | 4.84 | .321 | 1.40 | 9.4 | 3.3 | 4.7 | 230.2 | 239 | 136 | 124 | 26 | 85 | 121 | 9 | 0 | 0 | 1 | 13 | 3 | 4 | 4.57 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 31 | 31 | 10 | 13 | 4.82 | .342 | 1.55 | 9.2 | 4.7 | 4.3 | 224.0 | 230 | 127 | 120 | 21 | 118 | 106 | 8 | 0 | 0 | 1 | 14 | 2 | 5 | 4.88 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 88 | 0 | 8 | 9 | 4.34 | .304 | 1.31 | 7.7 | 4.1 | 10.2 | 112.0 | 96 | 57 | 54 | 14 | 51 | 127 | 0 | 15 | 9 | 0 | 0 | 0 | 6 | 3.72 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 69 | 0 | 7 | 6 | 3.16 | .264 | 1.04 | 6.5 | 3.0 | 8.8 | 85.1 | 61 | 31 | 30 | 10 | 28 | 83 | 0 | 11 | 1 | 0 | 0 | 3 | 5 | 3.67 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 47 | 0 | 2 | 6 | 1.98 | .303 | 1.31 | 7.2 | 4.6 | 5.5 | 59.0 | 47 | 15 | 13 | 4 | 30 | 36 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.19 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 33 | 0 | 2 | 1 | 2.34 | .262 | 1.06 | 6.9 | 2.8 | 7.7 | 42.1 | 32 | 11 | 11 | 2 | 13 | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.83 |