| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 13 | 13 | 4 | 6 | 4.28 | .268 | 1.09 | 8.6 | 1.2 | 4.3 | 88.1 | 84 | 43 | 42 | 13 | 12 | 42 | 2 | 0 | 0 | 0 | 7 | 1 | 2 | 4.41 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 26 | 0 | 2 | 2 | 2.13 | .296 | 1.22 | 6.8 | 4.3 | 11.9 | 25.1 | 19 | 6 | 6 | 1 | 12 | 33 | 0 | 16 | 0 | 0 | 0 | 1 | 0 | 2.44 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 24 | 0 | 1 | 2 | 6.86 | .351 | 1.57 | 9.9 | 4.3 | 9.4 | 21.0 | 23 | 18 | 16 | 9 | 10 | 22 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 8.05 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 26 | 0 | 3 | 0 | 3.69 | .258 | 1.01 | 7.0 | 2.3 | 8.7 | 31.2 | 24 | 13 | 13 | 4 | 8 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.61 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 18 | 0 | 0 | 2 | 5.49 | .385 | 1.88 | 13.3 | 4.3 | 6.6 | 19.2 | 28 | 12 | 12 | 0 | 9 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.95 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 10 | 0 | 0 | 0 | 3.18 | .261 | 1.06 | 8.2 | 1.6 | 4.1 | 11.1 | 10 | 4 | 4 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.82 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 11 | 0 | 2 | 0 | 7.82 | .433 | 2.21 | 14.3 | 6.8 | 6.0 | 12.2 | 19 | 11 | 11 | 3 | 9 | 8 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 7.42 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 2 | 2 | 0 | 0 | 3.86 | .300 | 1.21 | 9.0 | 1.9 | 5.8 | 14.0 | 14 | 7 | 6 | 2 | 3 | 9 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.43 |