| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 20 | 20 | 8 | 8 | 4.04 | .297 | 1.23 | 8.4 | 2.7 | 9.2 | 129.1 | 120 | 63 | 58 | 15 | 39 | 132 | 1 | 0 | 0 | 0 | 12 | 5 | 0 | 3.49 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 19 | 19 | 4 | 8 | 4.30 | .333 | 1.47 | 8.8 | 4.6 | 5.1 | 146.2 | 142 | 77 | 70 | 13 | 74 | 83 | 3 | 0 | 0 | 1 | 9 | 4 | 5 | 4.62 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 18 | 18 | 7 | 8 | 4.19 | .321 | 1.39 | 9.1 | 3.4 | 6.4 | 126.2 | 128 | 61 | 59 | 7 | 48 | 89 | 2 | 0 | 0 | 0 | 11 | 4 | 5 | 3.55 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 47 | 0 | 3 | 3 | 3.00 | .278 | 1.14 | 8.1 | 2.1 | 7.6 | 51.0 | 46 | 17 | 17 | 3 | 12 | 43 | 0 | 9 | 2 | 0 | 0 | 1 | 0 | 2.84 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 5 | 0 | 0 | 1 | 5.68 | .367 | 1.58 | 9.0 | 6.0 | 6.0 | 6.1 | 6 | 4 | 4 | 0 | 4 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.17 |