| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 20 | 20 | 7 | 8 | 5.46 | .323 | 1.41 | 11.0 | 1.7 | 5.7 | 122.0 | 149 | 80 | 74 | 17 | 23 | 77 | 2 | 0 | 0 | 0 | 9 | 3 | 1 | 4.19 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 20 | 20 | 11 | 5 | 4.01 | .267 | 1.06 | 7.2 | 2.3 | 4.7 | 139.0 | 111 | 64 | 62 | 14 | 36 | 72 | 4 | 0 | 0 | 2 | 10 | 5 | 5 | 4.16 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 20 | 20 | 8 | 8 | 5.32 | .313 | 1.37 | 9.7 | 2.6 | 5.8 | 133.2 | 144 | 89 | 79 | 21 | 39 | 86 | 2 | 0 | 0 | 0 | 8 | 0 | 8 | 4.64 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 34 | 0 | 0 | 1 | 1.44 | .266 | 1.09 | 5.2 | 4.6 | 9.0 | 31.1 | 18 | 5 | 5 | 1 | 16 | 31 | 0 | 29 | 0 | 0 | 0 | 0 | 1 | 2.97 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 43 | 0 | 3 | 1 | 1.92 | .279 | 1.14 | 6.9 | 3.5 | 7.8 | 51.2 | 39 | 15 | 11 | 3 | 20 | 44 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.27 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 24 | 0 | 1 | 0 | 4.25 | .373 | 1.79 | 13.0 | 3.4 | 7.4 | 29.2 | 42 | 15 | 14 | 3 | 11 | 24 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.83 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 21 | 0 | 3 | 4 | 7.48 | .381 | 1.85 | 15.4 | 1.7 | 7.3 | 21.2 | 36 | 20 | 18 | 6 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.67 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 18 | 0 | 0 | 1 | 5.16 | .253 | 1.01 | 7.4 | 2.0 | 6.5 | 22.2 | 18 | 13 | 13 | 3 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 40 | 10 | 0 | 0 | 1 | 4.61 | .367 | 1.70 | 11.5 | 4.0 | 8.8 | 54.2 | 69 | 30 | 28 | 5 | 24 | 53 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.69 |