| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 8 | 8 | 6 | 2 | 2.78 | .298 | 1.27 | 8.3 | 3.1 | 7.9 | 55.0 | 51 | 17 | 17 | 2 | 19 | 48 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 2.76 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 8 | 8 | 3 | 3 | 3.00 | .267 | 1.07 | 7.7 | 2.0 | 3.2 | 54.0 | 46 | 19 | 18 | 4 | 12 | 19 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.98 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 8 | 8 | 2 | 5 | 6.59 | .320 | 1.39 | 10.8 | 1.8 | 7.2 | 41.0 | 49 | 30 | 30 | 8 | 8 | 33 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.59 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 8 | 8 | 3 | 3 | 3.78 | .312 | 1.32 | 7.7 | 4.1 | 7.0 | 50.0 | 43 | 22 | 21 | 4 | 23 | 39 | 1 | 0 | 0 | 0 | 3 | 2 | 1 | 3.98 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 45 | 5 | 5 | 1 | 1 | 5.82 | .381 | 1.80 | 9.9 | 6.9 | 6.9 | 21.2 | 23 | 14 | 14 | 1 | 16 | 16 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.52 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 23 | 0 | 1 | 0 | 0.55 | .214 | 0.82 | 4.1 | 3.3 | 7.1 | 33.0 | 15 | 2 | 2 | 0 | 12 | 26 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.52 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 18 | 0 | 2 | 1 | 1.14 | .202 | 0.76 | 5.9 | 1.2 | 7.0 | 23.2 | 15 | 4 | 3 | 2 | 3 | 18 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.96 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 13 | 0 | 1 | 0 | 2.84 | .345 | 1.58 | 10.5 | 4.5 | 8.3 | 12.2 | 14 | 4 | 4 | 2 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.83 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 8 | 0 | 0 | 0 | 1.64 | .233 | 0.91 | 4.9 | 3.3 | 5.7 | 11.0 | 6 | 2 | 2 | 2 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.18 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 7 | 0 | 1 | 0 | 3.77 | .338 | 1.53 | 6.4 | 7.7 | 7.1 | 14.1 | 10 | 9 | 6 | 2 | 12 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.86 |