| SP | Martinez, P.Martinez, Pedro >> | 33 | 1997 | R | 90 | 38 | 38 | 12 | 10 | 3.95 | .283 | 1.17 | 7.4 | 3.1 | 8.7 | 248.1 | 205 | 111 | 109 | 38 | 86 | 239 | 9 | 0 | 0 | 4 | 20 | 3 | 6 | 4.14 |
| SP | Scherzer, M.Scherzer, Max # >> | 38 | 2021 | R | 92 | 38 | 38 | 10 | 11 | 5.47 | .303 | 1.27 | 9.0 | 2.5 | 9.0 | 184.1 | 184 | 120 | 112 | 47 | 51 | 183 | 0 | 0 | 0 | 0 | 14 | 5 | 4 | 5.24 |
| SP | Roark, T.Roark, Tanner >> | 32 | 2013 | R | 92 | 36 | 36 | 19 | 7 | 4.09 | .296 | 1.24 | 9.0 | 2.2 | 6.3 | 218.0 | 217 | 104 | 99 | 39 | 53 | 153 | 1 | 0 | 0 | 0 | 20 | 5 | 0 | 4.72 |
| SP | Hermanson, D.Hermanson, Dustin >> | 32 | 1997 | R | 49 | 36 | 36 | 12 | 6 | 4.96 | .320 | 1.40 | 9.0 | 3.7 | 5.8 | 179.2 | 179 | 102 | 99 | 34 | 73 | 116 | 0 | 0 | 0 | 0 | 12 | 2 | 4 | 5.43 |
| CL | Urbina, U.Urbina, Ugueth >> | 30 | 1997 | R | 91 | 75 | 0 | 11 | 10 | 3.31 | .267 | 1.09 | 7.0 | 2.8 | 8.6 | 122.1 | 95 | 49 | 45 | 15 | 38 | 116 | 0 | 32 | 4 | 0 | 0 | 1 | 1 | 3.66 |
| RP | Wetteland, J.Wetteland, John >> | 33 | 1994 | R | 63 | 100 | 0 | 10 | 3 | 3.68 | .290 | 1.23 | 6.8 | 4.3 | 6.4 | 110.0 | 83 | 45 | 45 | 19 | 52 | 78 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 5.25 |
| RP | Stewart, S.Stewart, Scott # >> | 29 | 2002 | L | 75 | 96 | 0 | 6 | 1 | 4.67 | .307 | 1.30 | 9.4 | 2.4 | 8.3 | 61.2 | 64 | 37 | 32 | 12 | 16 | 56 | 0 | 3 | 4 | 0 | 0 | 2 | 2 | 4.61 |
| SP | Perez, P.Perez, Pascual >> | 30 | 1987 | R | 70 | 32 | 32 | 9 | 12 | 5.39 | .327 | 1.44 | 9.6 | 3.4 | 5.6 | 170.1 | 181 | 106 | 102 | 34 | 64 | 105 | 3 | 0 | 0 | 1 | 13 | 3 | 1 | 5.55 |
| RP | Reardon, J.Reardon, Jeff >> | 31 | 1982 | R | 50 | 12 | 0 | 0 | 0 | 6.88 | .292 | 1.24 | 10.6 | 0.5 | 4.2 | 17.0 | 20 | 14 | 13 | 6 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.82 |