| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 21 | 21 | 10 | 9 | 3.95 | .306 | 1.31 | 7.3 | 4.5 | 8.5 | 132.0 | 107 | 61 | 58 | 12 | 66 | 125 | 0 | 0 | 0 | 0 | 11 | 2 | 2 | 3.83 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 20 | 20 | 6 | 6 | 5.68 | .341 | 1.54 | 11.0 | 2.9 | 5.3 | 123.2 | 151 | 80 | 78 | 17 | 40 | 72 | 0 | 0 | 0 | 0 | 9 | 1 | 0 | 4.63 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 19 | 19 | 8 | 2 | 4.95 | .338 | 1.50 | 7.5 | 6.0 | 7.5 | 111.0 | 92 | 63 | 61 | 18 | 74 | 93 | 0 | 0 | 0 | 0 | 8 | 4 | 1 | 5.54 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 36 | 0 | 1 | 3 | 3.86 | .276 | 1.14 | 5.4 | 4.9 | 7.5 | 35.0 | 21 | 15 | 15 | 4 | 19 | 29 | 0 | 29 | 3 | 0 | 0 | 0 | 0 | 4.46 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 41 | 0 | 3 | 1 | 3.00 | .301 | 1.29 | 7.4 | 4.2 | 9.6 | 45.0 | 37 | 17 | 15 | 4 | 21 | 48 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 3.42 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 44 | 0 | 5 | 0 | 3.78 | .315 | 1.36 | 7.9 | 4.3 | 7.2 | 50.0 | 44 | 21 | 21 | 3 | 24 | 40 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.68 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 28 | 0 | 0 | 1 | 5.34 | .344 | 1.53 | 8.0 | 6.1 | 12.9 | 28.2 | 25 | 17 | 17 | 4 | 19 | 40 | 0 | 0 | 1 | 0 | 0 | 1 | 7 | 4.14 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 28 | 0 | 5 | 2 | 6.51 | .336 | 1.45 | 9.3 | 4.0 | 10.0 | 27.2 | 28 | 21 | 20 | 9 | 12 | 30 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 6.67 |