| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 14 | 14 | 5 | 6 | 4.61 | .308 | 1.29 | 8.4 | 3.3 | 7.3 | 93.2 | 87 | 48 | 48 | 13 | 34 | 75 | 2 | 0 | 0 | 1 | 6 | 4 | 0 | 4.43 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 14 | 14 | 7 | 5 | 3.94 | .318 | 1.40 | 10.7 | 1.9 | 5.3 | 93.2 | 111 | 44 | 41 | 6 | 20 | 55 | 2 | 0 | 0 | 1 | 9 | 0 | 4 | 3.30 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 14 | 14 | 3 | 7 | 6.04 | .366 | 1.73 | 11.3 | 4.2 | 7.8 | 85.0 | 107 | 58 | 57 | 11 | 40 | 74 | 2 | 0 | 0 | 0 | 4 | 0 | 2 | 4.35 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 37 | 0 | 3 | 3 | 3.32 | .286 | 1.18 | 6.9 | 3.7 | 7.5 | 65.0 | 50 | 24 | 24 | 6 | 27 | 54 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 3.83 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 18 | 0 | 3 | 0 | 1.33 | .289 | 1.22 | 7.3 | 3.7 | 4.3 | 27.0 | 22 | 12 | 4 | 2 | 11 | 13 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 4.22 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 10 | 0 | 0 | 0 | 0.73 | .229 | 0.89 | 6.8 | 1.5 | 10.5 | 12.1 | 9 | 1 | 1 | 0 | 2 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1.17 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 60 | 1 | 0 | 0 | 0 | 0.00 | .222 | 0.64 | 4.5 | 2.3 | 4.5 | 4.2 | 2 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.50 |