| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 20 | 20 | 9 | 7 | 2.90 | .267 | 1.08 | 7.1 | 2.6 | 8.1 | 136.2 | 107 | 46 | 44 | 14 | 40 | 122 | 3 | 0 | 0 | 1 | 15 | 2 | 3 | 3.47 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 19 | 19 | 7 | 7 | 3.06 | .294 | 1.22 | 7.2 | 3.9 | 4.6 | 126.2 | 101 | 48 | 43 | 10 | 54 | 65 | 0 | 0 | 0 | 0 | 15 | 3 | 1 | 4.36 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 19 | 19 | 10 | 7 | 4.94 | .320 | 1.39 | 9.1 | 3.5 | 6.6 | 114.2 | 115 | 67 | 63 | 20 | 44 | 83 | 2 | 0 | 0 | 0 | 8 | 3 | 2 | 5.06 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 66 | 18 | 17 | 6 | 7 | 4.40 | .318 | 1.39 | 9.0 | 3.6 | 6.4 | 106.1 | 106 | 57 | 52 | 12 | 42 | 75 | 2 | 0 | 0 | 0 | 10 | 1 | 2 | 4.27 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 45 | 0 | 6 | 0 | 2.26 | .254 | 0.99 | 5.7 | 3.3 | 10.0 | 55.2 | 35 | 16 | 14 | 5 | 20 | 61 | 0 | 1 | 3 | 0 | 0 | 2 | 3 | 3.16 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 40 | 0 | 1 | 0 | 2.44 | .286 | 1.20 | 5.3 | 5.6 | 8.8 | 51.2 | 30 | 15 | 14 | 2 | 32 | 50 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 3.43 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 36 | 0 | 4 | 1 | 2.89 | .234 | 0.92 | 6.3 | 2.1 | 7.5 | 43.2 | 30 | 14 | 14 | 5 | 10 | 36 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.53 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 32 | 25 | 0 | 4 | 2 | 4.30 | .273 | 1.06 | 5.6 | 4.0 | 7.8 | 29.1 | 18 | 14 | 14 | 3 | 13 | 25 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.17 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 41 | 0 | 0 | 1 | 1.77 | .222 | 0.85 | 5.0 | 2.8 | 7.6 | 45.2 | 25 | 9 | 9 | 6 | 14 | 38 | 0 | 28 | 1 | 0 | 0 | 0 | 1 | 3.98 |