| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 21 | 21 | 12 | 5 | 3.64 | .312 | 1.33 | 9.1 | 3.0 | 8.2 | 150.2 | 151 | 62 | 61 | 17 | 50 | 136 | 1 | 0 | 0 | 0 | 14 | 4 | 4 | 3.74 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 20 | 20 | 7 | 5 | 5.00 | .320 | 1.40 | 9.6 | 3.0 | 5.1 | 135.0 | 144 | 76 | 75 | 18 | 45 | 76 | 3 | 0 | 0 | 1 | 7 | 2 | 4 | 4.65 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 50 | 0 | 6 | 4 | 3.56 | .288 | 1.16 | 7.1 | 3.3 | 11.4 | 68.1 | 54 | 29 | 27 | 11 | 25 | 86 | 0 | 2 | 0 | 0 | 0 | 4 | 2 | 3.85 |
| CL | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 43 | 0 | 3 | 4 | 2.91 | .287 | 1.21 | 7.0 | 3.9 | 9.4 | 46.1 | 36 | 15 | 15 | 6 | 20 | 48 | 0 | 20 | 5 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 38 | 0 | 2 | 0 | 3.02 | .270 | 1.11 | 7.7 | 2.5 | 8.4 | 47.2 | 40 | 16 | 16 | 8 | 13 | 44 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 23 | 0 | 0 | 1 | 5.01 | .300 | 1.29 | 9.4 | 2.3 | 7.4 | 23.1 | 24 | 13 | 13 | 2 | 6 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.26 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 20 | 0 | 0 | 2 | 4.74 | .360 | 1.68 | 9.9 | 5.2 | 10.4 | 19.0 | 21 | 12 | 10 | 2 | 11 | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.79 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 5 | 0 | 1 | 0 | 1.42 | .240 | 0.95 | 3.0 | 6.0 | 9.0 | 6.1 | 2 | 1 | 1 | 1 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.17 |