| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 21 | 21 | 10 | 8 | 3.81 | .268 | 1.09 | 7.8 | 2.0 | 7.3 | 146.1 | 127 | 62 | 62 | 8 | 32 | 119 | 4 | 0 | 0 | 1 | 12 | 2 | 4 | 2.78 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 20 | 20 | 7 | 5 | 3.22 | .274 | 1.10 | 6.9 | 3.0 | 4.0 | 137.0 | 105 | 55 | 49 | 8 | 46 | 61 | 0 | 0 | 0 | 0 | 13 | 4 | 4 | 3.96 |
| SP | Johnson, R.Johnson, Randy † # >> | 41 | 2004 | L | 83 | 20 | 20 | 12 | 5 | 3.07 | .263 | 1.04 | 7.0 | 2.5 | 8.1 | 143.2 | 111 | 50 | 49 | 12 | 39 | 129 | 1 | 0 | 0 | 0 | 14 | 4 | 1 | 3.19 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 14 | 14 | 8 | 3 | 3.57 | .292 | 1.20 | 6.6 | 4.3 | 3.2 | 90.2 | 66 | 37 | 36 | 7 | 43 | 32 | 2 | 0 | 0 | 1 | 8 | 3 | 0 | 4.83 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 15 | 12 | 10 | 2 | 4.11 | .315 | 1.37 | 7.9 | 4.4 | 6.8 | 92.0 | 81 | 45 | 42 | 6 | 45 | 69 | 0 | 0 | 0 | 0 | 5 | 1 | 3 | 3.85 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 40 | 0 | 1 | 2 | 0.97 | .210 | 0.80 | 5.3 | 2.0 | 5.9 | 46.1 | 27 | 5 | 5 | 2 | 10 | 30 | 0 | 27 | 1 | 0 | 0 | 0 | 0 | 2.91 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 43 | 0 | 3 | 4 | 3.38 | .280 | 1.17 | 7.7 | 2.8 | 10.9 | 48.0 | 41 | 19 | 18 | 9 | 15 | 58 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.96 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 33 | 0 | 2 | 1 | 2.14 | .252 | 1.01 | 4.6 | 4.6 | 7.9 | 33.2 | 17 | 8 | 8 | 1 | 17 | 29 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.18 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 18 | 0 | 0 | 1 | 2.55 | .254 | 0.96 | 6.9 | 2.1 | 7.9 | 17.2 | 13 | 5 | 5 | 1 | 4 | 15 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.88 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 9 | 6 | 4 | 3 | 5.59 | .336 | 1.50 | 10.6 | 3.1 | 5.3 | 46.2 | 54 | 29 | 29 | 3 | 16 | 27 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 3.78 |