| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 21 | 21 | 14 | 5 | 2.52 | .267 | 1.04 | 7.4 | 2.0 | 9.1 | 146.2 | 120 | 45 | 41 | 16 | 33 | 147 | 1 | 0 | 0 | 1 | 16 | 7 | 0 | 3.23 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 20 | 20 | 5 | 8 | 4.40 | .332 | 1.45 | 9.3 | 3.7 | 5.0 | 131.0 | 136 | 67 | 64 | 9 | 54 | 73 | 5 | 0 | 0 | 0 | 9 | 5 | 2 | 4.13 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 19 | 19 | 8 | 5 | 4.38 | .300 | 1.25 | 8.4 | 2.9 | 6.7 | 129.1 | 120 | 66 | 63 | 14 | 42 | 96 | 4 | 0 | 0 | 0 | 8 | 4 | 4 | 3.99 |
| SP | Drysdale, D.Drysdale, Don # >> | 28 | 1964 | R | 59 | 19 | 19 | 8 | 9 | 4.19 | .299 | 1.25 | 8.5 | 2.7 | 5.8 | 135.1 | 128 | 68 | 63 | 14 | 41 | 87 | 5 | 0 | 0 | 0 | 8 | 4 | 3 | 4.06 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 26 | 0 | 2 | 1 | 2.62 | .270 | 1.08 | 7.1 | 2.6 | 7.1 | 34.1 | 27 | 10 | 10 | 4 | 10 | 27 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 19 | 0 | 1 | 1 | 2.57 | .276 | 1.10 | 5.1 | 4.7 | 3.9 | 21.0 | 12 | 6 | 6 | 1 | 11 | 9 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 4.48 |