| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 20 | 20 | 6 | 12 | 3.45 | .282 | 1.14 | 7.8 | 2.4 | 8.1 | 156.1 | 136 | 66 | 60 | 16 | 42 | 140 | 8 | 0 | 0 | 2 | 14 | 6 | 2 | 3.46 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 19 | 19 | 4 | 12 | 5.54 | .320 | 1.37 | 9.9 | 2.4 | 8.3 | 133.1 | 147 | 83 | 82 | 18 | 36 | 122 | 2 | 0 | 0 | 0 | 5 | 5 | 6 | 3.85 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 19 | 19 | 7 | 10 | 4.01 | .291 | 1.20 | 8.1 | 2.7 | 5.0 | 143.2 | 129 | 74 | 64 | 15 | 43 | 79 | 3 | 0 | 0 | 0 | 10 | 5 | 1 | 4.27 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 19 | 19 | 8 | 7 | 4.55 | .335 | 1.46 | 9.3 | 3.9 | 4.6 | 146.1 | 151 | 75 | 74 | 15 | 63 | 74 | 5 | 0 | 0 | 1 | 7 | 7 | 6 | 4.76 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 49 | 0 | 4 | 1 | 3.95 | .260 | 1.04 | 6.9 | 2.4 | 9.2 | 57.0 | 44 | 29 | 25 | 8 | 15 | 58 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 3.63 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 26 | 0 | 1 | 2 | 8.27 | .398 | 1.84 | 11.3 | 5.9 | 5.4 | 20.2 | 25 | 23 | 19 | 6 | 13 | 12 | 0 | 3 | 0 | 0 | 0 | 3 | 0 | 8.10 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 14 | 0 | 0 | 1 | 3.68 | .302 | 1.23 | 7.7 | 3.9 | 11.6 | 14.2 | 12 | 6 | 6 | 0 | 6 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1.93 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |