| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 25 | 25 | 10 | 9 | 4.32 | .297 | 1.24 | 7.9 | 3.3 | 8.5 | 170.2 | 149 | 85 | 82 | 26 | 63 | 160 | 5 | 0 | 0 | 1 | 12 | 4 | 5 | 4.29 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 24 | 24 | 9 | 5 | 3.81 | .296 | 1.24 | 7.6 | 3.6 | 5.4 | 149.0 | 125 | 63 | 63 | 10 | 60 | 89 | 1 | 0 | 0 | 1 | 16 | 3 | 3 | 3.95 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 24 | 24 | 10 | 6 | 4.03 | .292 | 1.22 | 8.7 | 2.3 | 3.8 | 156.1 | 151 | 73 | 70 | 10 | 40 | 66 | 5 | 0 | 0 | 1 | 15 | 2 | 1 | 3.79 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 22 | 22 | 12 | 4 | 3.69 | .285 | 1.16 | 7.8 | 2.6 | 4.8 | 134.0 | 116 | 57 | 55 | 9 | 39 | 71 | 1 | 0 | 0 | 0 | 15 | 5 | 0 | 3.80 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 73 | 0 | 4 | 1 | 2.44 | .271 | 1.09 | 7.1 | 2.8 | 9.9 | 62.2 | 49 | 19 | 17 | 7 | 19 | 68 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 3.29 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 50 | 0 | 6 | 2 | 6.27 | .302 | 1.30 | 8.8 | 3.0 | 3.7 | 51.2 | 50 | 37 | 36 | 12 | 17 | 21 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 6.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 72 | 0 | 1 | 3 | 3.33 | .311 | 1.33 | 8.8 | 3.2 | 8.2 | 54.0 | 53 | 26 | 20 | 4 | 19 | 49 | 0 | 5 | 2 | 0 | 0 | 1 | 5 | 3.26 |