| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 6 | 4 | 5.09 | .297 | 1.26 | 8.8 | 2.6 | 9.7 | 86.2 | 84 | 54 | 49 | 12 | 25 | 93 | 0 | 0 | 0 | 0 | 9 | 1 | 0 | 3.56 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 14 | 14 | 5 | 5 | 4.44 | .323 | 1.42 | 10.1 | 2.7 | 5.3 | 77.0 | 86 | 43 | 38 | 11 | 23 | 45 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.62 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 14 | 14 | 9 | 4 | 4.79 | .275 | 1.10 | 8.6 | 1.2 | 6.3 | 94.0 | 90 | 53 | 50 | 18 | 13 | 66 | 2 | 0 | 0 | 0 | 5 | 4 | 0 | 4.63 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 47 | 0 | 6 | 1 | 6.58 | .355 | 1.63 | 8.3 | 6.5 | 8.8 | 53.1 | 49 | 41 | 39 | 9 | 38 | 52 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 5.45 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 42 | 0 | 1 | 4 | 5.44 | .377 | 1.79 | 10.5 | 5.9 | 8.6 | 49.2 | 57 | 37 | 30 | 4 | 32 | 47 | 0 | 1 | 4 | 0 | 0 | 1 | 3 | 4.16 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 43 | 0 | 4 | 0 | 4.79 | .325 | 1.43 | 7.9 | 5.0 | 9.6 | 47.0 | 41 | 31 | 25 | 8 | 26 | 50 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 4.81 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 39 | 0 | 3 | 4 | 4.57 | .299 | 1.28 | 8.3 | 3.3 | 8.6 | 41.1 | 38 | 21 | 21 | 10 | 15 | 39 | 0 | 19 | 2 | 0 | 0 | 0 | 0 | 5.37 |