| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 22 | 22 | 8 | 11 | 4.20 | .287 | 1.19 | 7.3 | 3.4 | 5.2 | 167.1 | 135 | 82 | 78 | 12 | 64 | 96 | 10 | 0 | 0 | 1 | 12 | 3 | 2 | 3.99 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 22 | 22 | 12 | 7 | 4.28 | .314 | 1.35 | 8.7 | 3.5 | 5.3 | 164.0 | 158 | 83 | 78 | 18 | 63 | 96 | 6 | 0 | 0 | 2 | 11 | 4 | 2 | 4.48 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 21 | 21 | 8 | 9 | 3.53 | .288 | 1.20 | 8.5 | 2.3 | 5.7 | 153.0 | 145 | 61 | 60 | 20 | 39 | 97 | 2 | 0 | 0 | 0 | 14 | 2 | 0 | 4.24 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 21 | 21 | 4 | 12 | 5.65 | .348 | 1.59 | 10.0 | 4.3 | 5.8 | 145.0 | 161 | 93 | 91 | 19 | 69 | 93 | 1 | 0 | 0 | 0 | 7 | 2 | 0 | 4.89 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 54 | 0 | 3 | 5 | 3.50 | .314 | 1.36 | 8.5 | 3.8 | 7.3 | 69.1 | 65 | 28 | 27 | 6 | 29 | 56 | 0 | 7 | 2 | 0 | 0 | 1 | 2 | 3.81 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 45 | 0 | 0 | 4 | 4.56 | .299 | 1.28 | 7.7 | 3.9 | 8.1 | 49.1 | 42 | 25 | 25 | 3 | 21 | 44 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 3.29 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 35 | 0 | 2 | 0 | 2.33 | .288 | 1.19 | 5.2 | 5.7 | 7.3 | 38.2 | 22 | 11 | 10 | 3 | 24 | 31 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 4.37 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 21 | 0 | 1 | 0 | 4.35 | .340 | 1.52 | 10.7 | 2.9 | 7.5 | 31.0 | 37 | 15 | 15 | 3 | 10 | 26 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.65 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 47 | 13 | 0 | 0 | 3 | 7.48 | .420 | 2.12 | 14.1 | 5.6 | 6.9 | 21.2 | 33 | 20 | 18 | 4 | 13 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.95 |