| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 17 | 17 | 9 | 5 | 3.33 | .291 | 1.20 | 8.9 | 1.9 | 8.4 | 135.0 | 134 | 53 | 50 | 15 | 28 | 126 | 6 | 0 | 0 | 1 | 10 | 4 | 1 | 3.29 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 17 | 17 | 8 | 4 | 4.00 | .310 | 1.32 | 8.4 | 3.5 | 8.3 | 117.0 | 109 | 58 | 52 | 11 | 46 | 108 | 1 | 0 | 0 | 1 | 9 | 3 | 7 | 3.63 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 16 | 16 | 3 | 11 | 5.45 | .345 | 1.56 | 10.7 | 3.3 | 4.5 | 109.0 | 130 | 68 | 66 | 11 | 40 | 55 | 2 | 0 | 0 | 1 | 6 | 2 | 4 | 4.46 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 16 | 16 | 4 | 11 | 6.09 | .366 | 1.69 | 11.5 | 3.7 | 5.4 | 106.1 | 136 | 80 | 72 | 16 | 44 | 64 | 1 | 0 | 0 | 0 | 5 | 4 | 2 | 5.11 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 16 | 16 | 6 | 8 | 4.79 | .320 | 1.38 | 8.7 | 3.8 | 7.6 | 99.2 | 96 | 58 | 53 | 15 | 42 | 84 | 0 | 0 | 0 | 0 | 8 | 3 | 5 | 4.64 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 43 | 0 | 3 | 2 | 3.72 | .254 | 1.02 | 7.9 | 1.5 | 8.7 | 55.2 | 48 | 26 | 23 | 3 | 9 | 53 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 2.27 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 41 | 0 | 1 | 0 | 4.56 | .314 | 1.37 | 7.1 | 5.4 | 8.0 | 47.1 | 37 | 24 | 24 | 9 | 28 | 42 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5.49 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 25 | 0 | 0 | 2 | 6.48 | .364 | 1.72 | 9.4 | 6.1 | 8.3 | 25.0 | 26 | 18 | 18 | 6 | 17 | 23 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 6.32 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 14 | 0 | 1 | 1 | 4.34 | .291 | 1.18 | 9.0 | 2.0 | 6.5 | 18.2 | 18 | 9 | 9 | 3 | 4 | 13 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.56 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 5 | 0 | 1 | 0 | 7.30 | .339 | 1.54 | 11.3 | 3.0 | 8.3 | 12.1 | 15 | 10 | 10 | 5 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.58 |