| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 16 | 16 | 10 | 4 | 4.21 | .305 | 1.32 | 9.3 | 2.6 | 9.9 | 104.2 | 108 | 50 | 49 | 11 | 30 | 114 | 0 | 0 | 0 | 0 | 8 | 0 | 3 | 3.05 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 16 | 16 | 4 | 7 | 4.30 | .307 | 1.32 | 10.0 | 2.0 | 5.3 | 106.2 | 118 | 57 | 51 | 12 | 23 | 62 | 3 | 0 | 0 | 1 | 7 | 1 | 1 | 3.98 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 6 | 6 | 3 | 1 | 5.18 | .372 | 1.78 | 10.4 | 5.6 | 4.5 | 40.0 | 46 | 24 | 23 | 2 | 25 | 20 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.53 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 32 | 0 | 4 | 7 | 4.10 | .287 | 1.21 | 6.8 | 4.1 | 9.7 | 37.1 | 28 | 21 | 17 | 5 | 17 | 40 | 0 | 15 | 3 | 0 | 0 | 0 | 0 | 3.97 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 29 | 0 | 1 | 2 | 3.71 | .306 | 1.32 | 9.3 | 2.6 | 8.5 | 34.0 | 35 | 20 | 14 | 5 | 10 | 32 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 38 | 0 | 2 | 1 | 4.26 | .337 | 1.50 | 8.8 | 4.7 | 6.2 | 38.0 | 37 | 18 | 18 | 6 | 20 | 26 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.34 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 29 | 0 | 2 | 2 | 3.09 | .304 | 1.31 | 7.0 | 4.8 | 8.2 | 32.0 | 25 | 11 | 11 | 1 | 17 | 29 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 3.19 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 22 | 0 | 0 | 0 | 5.25 | .314 | 1.38 | 9.4 | 3.0 | 6.4 | 24.0 | 25 | 14 | 14 | 6 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.83 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 12 | 7 | 5 | 2 | 5.66 | .332 | 1.44 | 9.8 | 3.3 | 2.9 | 55.2 | 60 | 37 | 35 | 7 | 20 | 18 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 5.25 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 47 | 5 | 3 | 1 | 1 | 5.68 | .374 | 1.79 | 10.9 | 5.2 | 7.1 | 19.0 | 23 | 12 | 12 | 3 | 11 | 15 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 5.21 |