| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 26 | 25 | 7 | 8 | 4.91 | .328 | 1.45 | 9.6 | 3.4 | 6.6 | 141.0 | 150 | 82 | 77 | 13 | 54 | 104 | 2 | 0 | 0 | 1 | 11 | 2 | 5 | 3.91 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 86 | 24 | 24 | 8 | 8 | 2.80 | .236 | 0.90 | 6.7 | 1.4 | 3.8 | 177.0 | 132 | 61 | 55 | 15 | 28 | 75 | 2 | 0 | 0 | 2 | 19 | 4 | 2 | 3.80 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 23 | 23 | 12 | 5 | 3.78 | .285 | 1.16 | 8.6 | 1.8 | 3.6 | 152.1 | 146 | 65 | 64 | 10 | 31 | 60 | 3 | 0 | 0 | 0 | 12 | 5 | 0 | 3.78 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 67 | 0 | 0 | 4 | 3.81 | .272 | 1.09 | 6.6 | 3.2 | 8.3 | 87.1 | 64 | 37 | 37 | 11 | 31 | 80 | 0 | 10 | 2 | 0 | 0 | 3 | 0 | 3.98 |
| RP | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 84 | 41 | 0 | 7 | 2 | 2.17 | .260 | 1.04 | 7.0 | 2.3 | 8.0 | 54.0 | 42 | 13 | 13 | 4 | 14 | 48 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 3.02 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 31 | 0 | 4 | 5 | 3.34 | .305 | 1.29 | 9.0 | 2.6 | 8.5 | 35.0 | 35 | 15 | 13 | 4 | 10 | 33 | 0 | 3 | 1 | 0 | 0 | 1 | 5 | 3.54 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 23 | 0 | 6 | 1 | 1.94 | .261 | 1.04 | 6.2 | 3.3 | 6.4 | 55.2 | 38 | 12 | 12 | 3 | 20 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.44 |