| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 12 | 12 | 3 | 1 | 3.58 | .282 | 1.12 | 6.8 | 3.3 | 9.8 | 65.1 | 49 | 26 | 26 | 11 | 24 | 71 | 0 | 0 | 0 | 0 | 7 | 4 | 3 | 4.31 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 96 | 11 | 11 | 5 | 4 | 5.00 | .328 | 1.44 | 10.7 | 2.3 | 11.2 | 54.0 | 64 | 32 | 30 | 12 | 14 | 67 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 4.24 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 11 | 11 | 2 | 3 | 3.86 | .279 | 1.15 | 8.3 | 2.1 | 10.1 | 65.1 | 60 | 29 | 28 | 11 | 15 | 73 | 1 | 0 | 0 | 0 | 7 | 1 | 3 | 3.69 |
| SP | Buchholz, C.Buchholz, Clay # >> | 29 | 2013 | R | 81 | 11 | 11 | 4 | 3 | 4.70 | .305 | 1.30 | 9.0 | 2.7 | 7.8 | 59.1 | 59 | 31 | 31 | 7 | 18 | 51 | 1 | 0 | 0 | 1 | 4 | 1 | 0 | 3.78 |
| SP | Foltynewicz, M.Foltynewicz, Michael # >> | 26 | 2018 | R | 67 | 11 | 11 | 3 | 4 | 4.84 | .364 | 1.61 | 9.2 | 5.4 | 10.1 | 48.1 | 49 | 27 | 26 | 6 | 29 | 54 | 0 | 0 | 0 | 0 | 5 | 5 | 2 | 4.50 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 30 | 0 | 2 | 4 | 3.32 | .274 | 1.11 | 7.9 | 2.3 | 10.8 | 40.2 | 35 | 15 | 15 | 8 | 10 | 48 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Robertson, D.Robertson, David >> | 32 | 2017 | R | 86 | 28 | 0 | 2 | 1 | 3.38 | .256 | 1.00 | 6.2 | 2.8 | 10.4 | 32.0 | 22 | 13 | 12 | 3 | 10 | 37 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 2.94 |
| RP | Parker, B.Parker, Blake >> | 32 | 2017 | R | 78 | 16 | 0 | 0 | 2 | 7.36 | .405 | 1.98 | 14.1 | 4.5 | 10.9 | 14.2 | 22 | 12 | 12 | 3 | 7 | 17 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 5.07 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 76 | 11 | 0 | 0 | 2 | 5.02 | .283 | 1.19 | 6.4 | 4.5 | 8.4 | 14.1 | 10 | 8 | 8 | 2 | 7 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.50 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 65 | 5 | 0 | 0 | 0 | 5.40 | .500 | 2.70 | 15.0 | 12.0 | 12.0 | 3.1 | 5 | 2 | 2 | 1 | 4 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 9.67 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 34 | 2014 | R | 47 | 3 | 0 | 0 | 0 | 4.50 | .200 | 0.75 | 6.8 | 0.0 | 4.5 | 4.0 | 3 | 2 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.50 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 46 | 5 | 0 | 1 | 0 | 0.00 | .278 | 1.15 | 2.3 | 9.0 | 11.3 | 4.1 | 1 | 0 | 0 | 0 | 4 | 5 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Hernandez, D.Hernandez, David >> | 27 | 2012 | R | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |