| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 20 | 20 | 9 | 8 | 3.38 | .273 | 1.11 | 7.2 | 2.8 | 8.4 | 146.1 | 117 | 61 | 55 | 25 | 45 | 136 | 4 | 0 | 0 | 1 | 12 | 3 | 0 | 4.35 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 20 | 20 | 9 | 7 | 4.92 | .326 | 1.43 | 9.3 | 3.6 | 8.1 | 130.0 | 134 | 76 | 71 | 19 | 52 | 117 | 0 | 0 | 0 | 0 | 10 | 3 | 4 | 4.37 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 19 | 19 | 8 | 9 | 4.62 | .312 | 1.35 | 9.4 | 2.7 | 3.7 | 142.1 | 149 | 79 | 73 | 16 | 43 | 59 | 7 | 0 | 0 | 0 | 8 | 2 | 3 | 4.58 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 19 | 19 | 6 | 7 | 4.65 | .315 | 1.37 | 9.6 | 2.8 | 6.5 | 131.2 | 140 | 69 | 68 | 13 | 41 | 95 | 1 | 0 | 0 | 1 | 9 | 1 | 6 | 3.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 32 | 0 | 3 | 1 | 2.48 | .259 | 1.02 | 6.8 | 2.5 | 7.8 | 36.1 | 27 | 10 | 10 | 2 | 10 | 31 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 2.92 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 13 | 0 | 0 | 2 | 3.86 | .276 | 1.14 | 7.7 | 2.6 | 5.8 | 14.0 | 12 | 6 | 6 | 2 | 4 | 9 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.43 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 2 | 0 | 0 | 0 | 0.00 | .125 | 0.43 | 0.0 | 4.5 | 0.0 | 2.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |