| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 32 | 32 | 9 | 16 | 5.48 | .325 | 1.41 | 9.8 | 3.0 | 8.5 | 226.2 | 245 | 150 | 138 | 40 | 75 | 213 | 9 | 0 | 0 | 2 | 13 | 7 | 6 | 4.50 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 31 | 31 | 15 | 14 | 3.92 | .276 | 1.12 | 7.5 | 2.6 | 3.5 | 236.2 | 197 | 106 | 103 | 26 | 69 | 93 | 10 | 0 | 0 | 3 | 15 | 4 | 2 | 4.57 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 29 | 29 | 11 | 9 | 4.98 | .338 | 1.51 | 9.0 | 4.6 | 4.2 | 195.0 | 196 | 111 | 108 | 22 | 99 | 90 | 1 | 0 | 0 | 0 | 12 | 4 | 3 | 5.13 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 80 | 0 | 6 | 4 | 3.93 | .284 | 1.17 | 8.2 | 2.4 | 8.3 | 91.2 | 83 | 42 | 40 | 8 | 24 | 84 | 0 | 8 | 4 | 0 | 0 | 2 | 0 | 3.15 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 68 | 0 | 9 | 3 | 3.43 | .276 | 1.12 | 7.8 | 2.3 | 7.6 | 86.2 | 75 | 38 | 33 | 11 | 22 | 73 | 0 | 8 | 0 | 0 | 0 | 2 | 3 | 3.80 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 56 | 0 | 5 | 3 | 4.90 | .320 | 1.40 | 9.3 | 3.4 | 7.6 | 64.1 | 66 | 37 | 35 | 10 | 24 | 54 | 0 | 10 | 1 | 0 | 0 | 1 | 2 | 4.52 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 2 | 0 | 0 | 0 | 21.60 | .583 | 4.20 | 54.0 | 9.0 | 18.0 | 1.2 | 6 | 4 | 4 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 19 | 0 | 3 | 1 | 5.91 | .338 | 1.53 | 10.7 | 3.1 | 7.6 | 32.0 | 38 | 21 | 21 | 9 | 11 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.00 |