| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 32 | 32 | 13 | 9 | 3.56 | .273 | 1.11 | 7.3 | 2.6 | 8.5 | 245.0 | 200 | 101 | 97 | 20 | 72 | 231 | 2 | 0 | 0 | 0 | 19 | 4 | 5 | 3.11 |
| SP | Mathewson, C.Mathewson, Christy † $$ >> | 28 | 1908 | R | 82 | 31 | 31 | 15 | 9 | 2.68 | .257 | 1.03 | 7.6 | 1.6 | 4.3 | 238.0 | 201 | 73 | 71 | 19 | 43 | 114 | 13 | 0 | 0 | 6 | 20 | 3 | 2 | 3.66 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 30 | 30 | 14 | 10 | 3.99 | .307 | 1.29 | 6.9 | 4.7 | 8.1 | 205.1 | 157 | 92 | 91 | 20 | 108 | 185 | 2 | 0 | 0 | 0 | 17 | 8 | 4 | 4.16 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 77 | 0 | 2 | 2 | 1.72 | .300 | 1.27 | 7.3 | 4.3 | 7.9 | 57.2 | 46 | 11 | 11 | 4 | 27 | 50 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Charlton, N.Charlton, Norm >> | 30 | 1993 | L | 31 | 92 | 0 | 3 | 3 | 2.15 | .329 | 1.45 | 5.9 | 7.2 | 9.2 | 50.1 | 33 | 12 | 12 | 4 | 40 | 51 | 0 | 3 | 2 | 0 | 0 | 1 | 6 | 4.46 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 12 | 0 | 3 | 0 | 0.00 | .200 | 0.75 | 1.5 | 6.0 | 6.0 | 6.2 | 1 | 0 | 0 | 0 | 4 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 44 | 12 | 0 | 1 | 0 | 1.69 | .289 | 1.22 | 7.2 | 4.5 | 11.7 | 10.2 | 8 | 2 | 2 | 1 | 5 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 16 | 0 | 4 | 1 | 0.44 | .184 | 0.68 | 4.5 | 1.8 | 4.5 | 20.2 | 10 | 1 | 1 | 0 | 4 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.60 |