| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 8 | 7 | 4.37 | .293 | 1.22 | 8.5 | 2.6 | 9.1 | 131.2 | 123 | 66 | 64 | 13 | 38 | 133 | 0 | 0 | 0 | 0 | 12 | 3 | 0 | 3.20 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 19 | 19 | 6 | 8 | 6.87 | .365 | 1.70 | 12.4 | 3.0 | 8.2 | 95.2 | 131 | 79 | 73 | 20 | 32 | 87 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.98 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 19 | 19 | 7 | 8 | 4.42 | .318 | 1.38 | 9.9 | 2.6 | 4.8 | 112.0 | 123 | 60 | 55 | 16 | 32 | 60 | 5 | 0 | 0 | 1 | 9 | 2 | 1 | 4.70 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 19 | 19 | 5 | 8 | 6.13 | .346 | 1.58 | 11.4 | 2.9 | 4.8 | 105.2 | 133 | 81 | 72 | 15 | 34 | 56 | 1 | 0 | 0 | 0 | 6 | 1 | 2 | 4.79 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 56 | 0 | 5 | 3 | 4.90 | .321 | 1.38 | 9.0 | 3.6 | 10.1 | 60.2 | 60 | 37 | 33 | 14 | 24 | 67 | 0 | 22 | 5 | 0 | 0 | 2 | 2 | 5.10 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 47 | 0 | 0 | 2 | 4.93 | .315 | 1.36 | 9.0 | 3.3 | 10.5 | 49.1 | 49 | 28 | 27 | 11 | 18 | 57 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 4.76 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 52 | 0 | 4 | 1 | 4.91 | .348 | 1.56 | 9.8 | 4.3 | 6.9 | 55.0 | 60 | 30 | 30 | 7 | 26 | 42 | 0 | 1 | 0 | 0 | 0 | 2 | 7 | 4.65 |