| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 98 | 21 | 21 | 10 | 7 | 3.69 | .305 | 1.31 | 8.8 | 3.0 | 7.2 | 153.2 | 150 | 66 | 63 | 14 | 51 | 122 | 7 | 0 | 0 | 1 | 12 | 1 | 4 | 3.61 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 20 | 20 | 9 | 6 | 4.05 | .296 | 1.26 | 7.7 | 3.6 | 4.7 | 126.2 | 108 | 59 | 57 | 3 | 51 | 66 | 4 | 0 | 0 | 2 | 11 | 1 | 2 | 3.50 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 19 | 19 | 6 | 6 | 3.99 | .286 | 1.18 | 7.7 | 2.9 | 6.7 | 124.0 | 106 | 60 | 55 | 12 | 40 | 92 | 6 | 0 | 0 | 1 | 10 | 3 | 5 | 3.81 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 47 | 0 | 8 | 1 | 2.45 | .267 | 1.08 | 6.4 | 3.4 | 10.6 | 69.2 | 49 | 21 | 19 | 3 | 26 | 81 | 0 | 2 | 3 | 0 | 0 | 1 | 5 | 2.39 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 29 | 0 | 1 | 2 | 3.82 | .271 | 1.12 | 8.3 | 1.9 | 4.4 | 37.2 | 34 | 17 | 16 | 4 | 8 | 18 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 26 | 0 | 3 | 1 | 3.52 | .333 | 1.47 | 6.6 | 6.9 | 11.4 | 30.2 | 22 | 12 | 12 | 4 | 23 | 38 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.60 |
| RP | Raymond, C.Raymond, Claude >> | 28 | 1965 | R | 6 | 22 | 0 | 1 | 3 | 3.41 | .319 | 1.38 | 10.0 | 2.4 | 4.9 | 37.0 | 41 | 18 | 14 | 1 | 10 | 20 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 3.16 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 7 | 0 | 0 | 1 | 7.36 | .405 | 1.91 | 7.7 | 10.3 | 6.4 | 7.1 | 6 | 7 | 6 | 0 | 8 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.43 |