| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 17 | 17 | 8 | 7 | 2.86 | .271 | 1.09 | 7.0 | 2.8 | 8.2 | 135.1 | 105 | 45 | 43 | 8 | 42 | 123 | 6 | 0 | 0 | 2 | 11 | 4 | 2 | 2.97 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 16 | 16 | 5 | 8 | 4.62 | .305 | 1.27 | 8.4 | 2.9 | 4.5 | 113.0 | 106 | 63 | 58 | 14 | 37 | 56 | 6 | 0 | 0 | 1 | 7 | 6 | 2 | 4.76 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 16 | 16 | 3 | 7 | 6.51 | .344 | 1.54 | 10.0 | 3.9 | 5.2 | 95.1 | 106 | 77 | 69 | 21 | 41 | 55 | 2 | 0 | 0 | 0 | 5 | 3 | 6 | 6.11 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 16 | 16 | 8 | 7 | 5.03 | .309 | 1.33 | 8.6 | 3.4 | 3.7 | 107.1 | 102 | 61 | 60 | 19 | 41 | 44 | 5 | 0 | 0 | 1 | 7 | 1 | 6 | 5.66 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 15 | 15 | 5 | 6 | 4.73 | .327 | 1.44 | 9.3 | 3.7 | 4.5 | 99.0 | 102 | 52 | 52 | 8 | 41 | 50 | 1 | 0 | 0 | 1 | 9 | 1 | 0 | 4.31 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 38 | 0 | 5 | 4 | 3.75 | .327 | 1.40 | 7.7 | 5.1 | 9.9 | 57.2 | 49 | 24 | 24 | 3 | 32 | 63 | 0 | 5 | 3 | 0 | 0 | 3 | 0 | 3.32 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 30 | 0 | 0 | 2 | 3.65 | .318 | 1.36 | 9.4 | 2.9 | 5.9 | 49.1 | 51 | 23 | 20 | 5 | 16 | 32 | 0 | 4 | 0 | 0 | 0 | 2 | 1 | 4.12 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 22 | 0 | 2 | 0 | 4.03 | .350 | 1.61 | 10.2 | 4.5 | 8.2 | 22.1 | 25 | 11 | 10 | 1 | 11 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.27 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 12 | 1 | 3 | 0 | 3.29 | .305 | 1.32 | 9.0 | 3.0 | 4.7 | 27.1 | 27 | 10 | 10 | 2 | 9 | 14 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 3.93 |