| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 10 | 10 | 5 | 4 | 3.53 | .295 | 1.26 | 7.5 | 3.8 | 3.5 | 74.0 | 62 | 31 | 29 | 5 | 31 | 29 | 2 | 0 | 0 | 0 | 6 | 0 | 2 | 4.35 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 10 | 10 | 3 | 4 | 5.38 | .313 | 1.35 | 8.6 | 3.5 | 4.4 | 77.0 | 74 | 50 | 46 | 7 | 30 | 38 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 4.40 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 9 | 9 | 1 | 5 | 6.90 | .380 | 1.80 | 10.6 | 5.8 | 8.8 | 45.2 | 53 | 36 | 35 | 9 | 29 | 44 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 5.71 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 25 | 0 | 3 | 0 | 1.86 | .211 | 0.80 | 4.7 | 2.6 | 6.9 | 38.2 | 20 | 8 | 8 | 1 | 11 | 29 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 26 | 0 | 1 | 2 | 3.19 | .268 | 1.10 | 5.8 | 4.1 | 4.9 | 31.0 | 20 | 14 | 11 | 3 | 14 | 17 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.52 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 15 | 0 | 0 | 2 | 7.50 | .372 | 1.78 | 12.0 | 4.0 | 7.0 | 18.0 | 24 | 19 | 15 | 3 | 8 | 14 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.94 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 9 | 0 | 2 | 0 | 4.24 | .346 | 1.59 | 9.5 | 4.8 | 9.0 | 17.0 | 18 | 9 | 8 | 2 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.12 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 1 | 1 | 0 | 3.52 | .410 | 1.96 | 12.9 | 6.4 | 3.9 | 7.2 | 10 | 6 | 3 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.71 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 3 | 0 | 0 | 1 | 15.43 | .563 | 3.86 | 31.5 | 9.0 | 0.0 | 2.1 | 7 | 4 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |