| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 10 | 10 | 0 | 6 | 4.30 | .308 | 1.32 | 8.0 | 4.1 | 9.8 | 60.2 | 53 | 32 | 29 | 11 | 27 | 65 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 4.62 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 10 | 10 | 4 | 4 | 4.38 | .292 | 1.21 | 7.2 | 3.7 | 4.9 | 76.0 | 61 | 41 | 37 | 11 | 31 | 41 | 4 | 0 | 0 | 1 | 4 | 2 | 1 | 5.11 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 10 | 9 | 2 | 6 | 4.91 | .357 | 1.62 | 10.5 | 4.1 | 9.4 | 66.0 | 77 | 39 | 36 | 15 | 30 | 69 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 5.36 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 27 | 0 | 0 | 1 | 5.47 | .288 | 1.22 | 8.6 | 2.6 | 9.8 | 24.2 | 23 | 15 | 15 | 7 | 7 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.50 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 17 | 0 | 4 | 1 | 1.59 | .239 | 0.94 | 5.3 | 3.2 | 9.0 | 17.0 | 10 | 4 | 3 | 0 | 6 | 17 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.06 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 26 | 0 | 1 | 0 | 2.45 | .276 | 1.09 | 7.5 | 2.5 | 4.0 | 18.1 | 15 | 9 | 5 | 2 | 5 | 8 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 4.56 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 2 | 0 | 0 | 0 | 5.40 | .375 | 1.80 | 15.0 | 3.0 | 9.0 | 3.1 | 5 | 2 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 2 | 0 | 0 | 0 | 10.80 | .500 | 3.00 | 36.0 | 9.0 | 27.0 | 1.2 | 4 | 2 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 7 | 0 | 0 | 0 | 3.68 | .333 | 1.50 | 10.3 | 3.9 | 9.0 | 7.1 | 8 | 3 | 3 | 1 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.14 |