| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 24 | 24 | 11 | 9 | 4.14 | .290 | 1.22 | 8.0 | 3.1 | 5.3 | 147.2 | 130 | 73 | 68 | 16 | 50 | 86 | 6 | 0 | 0 | 2 | 13 | 1 | 2 | 4.29 |
| SP | Richard, J.Richard, J.R. $ >> | 30 | 1980 | R | 90 | 24 | 24 | 9 | 8 | 4.32 | .312 | 1.35 | 7.9 | 4.3 | 7.2 | 145.2 | 127 | 78 | 70 | 16 | 69 | 116 | 2 | 0 | 0 | 1 | 14 | 2 | 4 | 4.30 |
| SP | Brown, M.Brown, Mordecai $ >> | 32 | 1908 | R | 85 | 23 | 23 | 10 | 6 | 3.14 | .281 | 1.15 | 7.5 | 2.9 | 5.1 | 152.0 | 126 | 55 | 53 | 6 | 49 | 86 | 2 | 0 | 0 | 1 | 16 | 3 | 4 | 3.41 |
| SP | Hill, R.Hill, Rich # $ >> | 36 | 2016 | L | 65 | 23 | 23 | 4 | 13 | 5.32 | .360 | 1.65 | 10.5 | 4.4 | 8.6 | 113.1 | 132 | 75 | 67 | 12 | 55 | 108 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 4.04 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 72 | 0 | 5 | 1 | 3.53 | .282 | 1.18 | 8.2 | 2.5 | 9.1 | 66.1 | 60 | 29 | 26 | 9 | 18 | 67 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 3.56 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 29 | 0 | 1 | 0 | 2.03 | .298 | 1.24 | 7.6 | 3.8 | 10.7 | 26.2 | 22 | 6 | 6 | 1 | 11 | 31 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 2.50 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 70 | 0 | 4 | 1 | 3.32 | .286 | 1.15 | 6.5 | 4.0 | 7.7 | 43.1 | 31 | 16 | 16 | 3 | 19 | 37 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.65 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 28 | 0 | 1 | 3 | 4.68 | .292 | 1.24 | 6.5 | 4.7 | 9.4 | 25.0 | 18 | 15 | 13 | 4 | 13 | 26 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.56 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 33 | 0 | 0 | 0 | 4.33 | .289 | 1.22 | 8.0 | 3.1 | 7.2 | 35.1 | 31 | 17 | 17 | 3 | 12 | 28 | 0 | 4 | 4 | 0 | 0 | 0 | 1 | 3.54 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 17 | 0 | 1 | 1 | 5.02 | .323 | 1.41 | 10.6 | 2.2 | 6.2 | 57.1 | 67 | 36 | 32 | 10 | 14 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.70 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 44 | 0 | 2 | 4 | 2.73 | .269 | 1.08 | 6.1 | 3.5 | 8.7 | 66.0 | 45 | 20 | 20 | 4 | 26 | 64 | 0 | 17 | 2 | 0 | 0 | 2 | 0 | 3.12 |