| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 16 | 16 | 8 | 4 | 3.10 | .262 | 1.05 | 5.7 | 3.8 | 7.1 | 122.0 | 77 | 42 | 42 | 9 | 51 | 96 | 2 | 0 | 0 | 0 | 11 | 2 | 2 | 3.69 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 17 | 16 | 5 | 3 | 2.75 | .270 | 1.09 | 7.8 | 2.0 | 4.9 | 121.0 | 105 | 37 | 37 | 7 | 27 | 66 | 1 | 0 | 0 | 1 | 12 | 2 | 0 | 3.38 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 16 | 16 | 5 | 7 | 3.37 | .271 | 1.09 | 8.0 | 1.9 | 6.1 | 125.2 | 111 | 48 | 47 | 12 | 26 | 85 | 1 | 0 | 0 | 0 | 9 | 3 | 1 | 3.58 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 16 | 16 | 5 | 5 | 4.75 | .311 | 1.31 | 7.3 | 4.6 | 8.3 | 96.2 | 78 | 51 | 51 | 11 | 49 | 88 | 1 | 0 | 0 | 0 | 9 | 4 | 2 | 4.31 |
| RP | Eckersley, D.Eckersley, Dennis † $ >> | 36 | 1990 | R | 88 | 47 | 0 | 9 | 3 | 2.76 | .259 | 1.05 | 8.0 | 1.6 | 7.2 | 45.2 | 40 | 15 | 14 | 3 | 8 | 36 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 2.80 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 77 | 32 | 0 | 4 | 2 | 4.67 | .341 | 1.56 | 7.3 | 6.7 | 7.3 | 27.0 | 22 | 15 | 14 | 7 | 20 | 22 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 6.96 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 17 | 0 | 1 | 0 | 2.25 | .238 | 0.94 | 5.6 | 2.8 | 3.4 | 16.0 | 10 | 4 | 4 | 2 | 5 | 6 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.81 |
| SP | Jenkins, F.Jenkins, Fergie >> | 29 | 1971 | R | 16 | 1 | 1 | 0 | 0 | 2.08 | .316 | 1.38 | 11.3 | 2.3 | 5.6 | 8.2 | 10 | 2 | 2 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.13 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 5 | 0 | 1 | 1 | 3.86 | .323 | 1.43 | 7.7 | 5.1 | 10.3 | 7.0 | 6 | 3 | 3 | 0 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.43 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 49 | 0 | 1 | 0 | 3.19 | .262 | 1.06 | 7.0 | 2.6 | 10.5 | 31.0 | 24 | 11 | 11 | 4 | 9 | 36 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.23 |