| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 13 | 13 | 4 | 7 | 5.18 | .326 | 1.41 | 9.5 | 3.3 | 8.1 | 80.0 | 84 | 49 | 46 | 15 | 29 | 72 | 0 | 0 | 0 | 0 | 6 | 3 | 4 | 4.84 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 13 | 3 | 7 | 3.58 | .281 | 1.15 | 7.5 | 2.8 | 5.1 | 93.0 | 78 | 39 | 37 | 10 | 29 | 53 | 4 | 0 | 0 | 1 | 8 | 2 | 1 | 4.26 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 13 | 13 | 7 | 4 | 5.47 | .331 | 1.47 | 9.4 | 3.8 | 5.2 | 82.1 | 86 | 51 | 50 | 16 | 35 | 47 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 5.71 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 12 | 12 | 4 | 7 | 5.37 | .364 | 1.70 | 9.5 | 6.0 | 2.8 | 68.2 | 72 | 45 | 41 | 2 | 45 | 21 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 4.79 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 58 | 13 | 12 | 6 | 5 | 3.94 | .308 | 1.32 | 8.9 | 3.1 | 6.1 | 91.1 | 90 | 45 | 40 | 12 | 31 | 62 | 5 | 0 | 0 | 2 | 6 | 1 | 0 | 4.41 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 32 | 0 | 1 | 3 | 3.72 | .286 | 1.18 | 8.3 | 2.4 | 9.6 | 48.1 | 44 | 26 | 20 | 5 | 13 | 51 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 3.10 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 33 | 0 | 1 | 2 | 6.21 | .347 | 1.59 | 10.5 | 4.1 | 7.5 | 37.2 | 43 | 26 | 26 | 7 | 17 | 31 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 5.16 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 19 | 0 | 1 | 1 | 4.26 | .352 | 1.58 | 9.9 | 4.3 | 8.5 | 19.0 | 21 | 11 | 9 | 0 | 9 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.68 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 16 | 0 | 0 | 0 | 3.95 | .317 | 1.32 | 9.7 | 2.8 | 12.5 | 13.2 | 14 | 6 | 6 | 1 | 4 | 18 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.38 |
| RP | McMahon, D.McMahon, Don >> | 37 | 1967 | R | 43 | 14 | 0 | 0 | 0 | 2.93 | .281 | 1.11 | 6.0 | 4.2 | 6.6 | 15.1 | 10 | 5 | 5 | 1 | 7 | 11 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.00 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 5 | 1 | 0 | 1 | 9.00 | .375 | 1.80 | 14.4 | 1.8 | 0.0 | 5.0 | 8 | 5 | 5 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 6.20 |