| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 13 | 13 | 4 | 7 | 4.45 | .303 | 1.28 | 9.5 | 2.0 | 9.4 | 85.0 | 90 | 47 | 42 | 14 | 19 | 89 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 3.79 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 13 | 13 | 9 | 2 | 2.78 | .273 | 1.09 | 6.3 | 3.4 | 7.1 | 94.0 | 66 | 31 | 29 | 8 | 36 | 74 | 1 | 0 | 0 | 0 | 10 | 4 | 0 | 3.81 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 13 | 13 | 6 | 5 | 5.35 | .331 | 1.45 | 9.9 | 3.2 | 7.4 | 77.1 | 85 | 47 | 46 | 10 | 27 | 63 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 4.22 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 12 | 12 | 6 | 5 | 3.97 | .292 | 1.21 | 7.6 | 3.3 | 8.1 | 79.1 | 67 | 36 | 35 | 10 | 29 | 71 | 1 | 0 | 0 | 1 | 6 | 2 | 1 | 4.03 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 12 | 12 | 3 | 2 | 6.20 | .366 | 1.70 | 11.2 | 4.2 | 5.8 | 65.1 | 81 | 45 | 45 | 8 | 30 | 42 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.78 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 24 | 0 | 0 | 0 | 1.61 | .221 | 0.81 | 6.1 | 1.2 | 10.2 | 22.1 | 15 | 4 | 4 | 3 | 3 | 25 | 0 | 21 | 0 | 0 | 0 | 1 | 0 | 3.05 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 26 | 0 | 1 | 3 | 5.47 | .295 | 1.25 | 8.7 | 2.8 | 11.1 | 26.1 | 25 | 18 | 16 | 4 | 8 | 32 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 3.46 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 34 | 0 | 1 | 2 | 4.46 | .327 | 1.43 | 10.3 | 2.8 | 9.0 | 36.1 | 41 | 18 | 18 | 8 | 11 | 36 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.89 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 30 | 0 | 2 | 2 | 2.17 | .275 | 1.10 | 7.1 | 2.8 | 11.5 | 29.0 | 23 | 13 | 7 | 0 | 9 | 37 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1.48 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 16 | 0 | 1 | 2 | 4.24 | .363 | 1.71 | 11.6 | 3.7 | 7.9 | 17.0 | 22 | 9 | 8 | 3 | 7 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.76 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 9 | 0 | 0 | 0 | 1.59 | .227 | 0.88 | 4.9 | 3.3 | 9.0 | 11.1 | 6 | 2 | 2 | 1 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 11 | 0 | 0 | 0 | 4.11 | .292 | 1.17 | 6.0 | 4.8 | 10.8 | 15.1 | 10 | 8 | 7 | 1 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.27 |