| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 17 | 17 | 4 | 9 | 3.98 | .291 | 1.20 | 9.0 | 1.8 | 4.4 | 124.1 | 124 | 61 | 55 | 13 | 25 | 60 | 1 | 0 | 0 | 0 | 9 | 4 | 1 | 4.10 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 17 | 16 | 4 | 8 | 4.66 | .321 | 1.39 | 9.6 | 2.9 | 5.4 | 102.1 | 109 | 57 | 53 | 12 | 33 | 61 | 0 | 0 | 1 | 0 | 9 | 3 | 2 | 4.39 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 11 | 11 | 3 | 6 | 5.50 | .325 | 1.42 | 9.8 | 3.0 | 3.4 | 75.1 | 82 | 52 | 46 | 7 | 25 | 28 | 2 | 0 | 0 | 0 | 2 | 2 | 1 | 4.55 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 99 | 32 | 0 | 3 | 4 | 2.55 | .321 | 1.42 | 8.5 | 4.4 | 7.5 | 35.1 | 33 | 10 | 10 | 4 | 17 | 29 | 0 | 17 | 0 | 0 | 0 | 0 | 1 | 4.29 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 37 | 0 | 4 | 0 | 2.38 | .250 | 1.00 | 5.8 | 3.2 | 7.1 | 34.0 | 22 | 10 | 9 | 2 | 12 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 40 | 0 | 2 | 1 | 3.04 | .238 | 0.94 | 5.2 | 3.5 | 8.3 | 26.2 | 15 | 9 | 9 | 5 | 10 | 24 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 4.81 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 22 | 0 | 2 | 0 | 2.16 | .275 | 1.14 | 6.2 | 4.5 | 11.3 | 16.2 | 11 | 5 | 4 | 1 | 8 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.81 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 10 | 4 | 1 | 1 | 6.31 | .319 | 1.35 | 10.3 | 2.0 | 5.3 | 41.1 | 47 | 29 | 29 | 10 | 9 | 24 | 1 | 1 | 0 | 0 | 1 | 2 | 0 | 5.80 |