| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 35 | 35 | 15 | 12 | 4.75 | .317 | 1.37 | 9.2 | 3.2 | 8.8 | 219.2 | 223 | 125 | 116 | 25 | 77 | 214 | 0 | 0 | 0 | 0 | 14 | 6 | 0 | 3.67 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 34 | 34 | 11 | 19 | 6.12 | .364 | 1.70 | 11.8 | 3.5 | 7.8 | 204.1 | 268 | 166 | 139 | 24 | 80 | 176 | 3 | 0 | 0 | 2 | 8 | 3 | 7 | 4.02 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 33 | 33 | 9 | 12 | 7.15 | .375 | 1.76 | 10.5 | 5.4 | 7.8 | 172.1 | 201 | 146 | 137 | 21 | 103 | 150 | 0 | 0 | 0 | 0 | 9 | 6 | 4 | 4.74 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 31 | 31 | 16 | 8 | 5.18 | .343 | 1.55 | 8.7 | 5.2 | 8.2 | 189.1 | 183 | 112 | 109 | 14 | 110 | 172 | 0 | 0 | 0 | 0 | 17 | 3 | 2 | 3.94 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 104 | 0 | 4 | 1 | 3.84 | .325 | 1.38 | 7.6 | 4.9 | 8.0 | 72.2 | 61 | 36 | 31 | 4 | 39 | 64 | 0 | 0 | 3 | 0 | 0 | 5 | 8 | 3.78 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 78 | 0 | 4 | 0 | 3.18 | .356 | 1.61 | 8.7 | 5.9 | 8.8 | 56.2 | 54 | 26 | 20 | 6 | 37 | 55 | 0 | 1 | 3 | 0 | 0 | 3 | 2 | 4.57 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 59 | 0 | 3 | 0 | 2.76 | .299 | 1.28 | 7.8 | 3.9 | 7.9 | 58.2 | 50 | 18 | 18 | 3 | 25 | 51 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.21 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 33 | 0 | 1 | 4 | 4.82 | .330 | 1.45 | 10.1 | 3.0 | 8.7 | 93.1 | 104 | 55 | 50 | 15 | 31 | 90 | 0 | 4 | 0 | 0 | 0 | 3 | 1 | 4.26 |