| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 20 | 20 | 5 | 11 | 3.66 | .308 | 1.31 | 7.7 | 4.1 | 9.1 | 123.0 | 105 | 51 | 50 | 17 | 56 | 125 | 0 | 0 | 0 | 0 | 12 | 3 | 1 | 4.20 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 19 | 19 | 1 | 5 | 4.52 | .319 | 1.36 | 9.1 | 3.3 | 7.1 | 77.2 | 78 | 39 | 39 | 12 | 28 | 61 | 0 | 0 | 0 | 0 | 1 | 3 | 4 | 4.65 |
| SP | Burnett, A.Burnett, A.J. # >> | 25 | 2002 | R | 57 | 18 | 18 | 9 | 5 | 5.71 | .346 | 1.56 | 8.4 | 5.8 | 8.5 | 97.2 | 90 | 66 | 62 | 21 | 62 | 92 | 0 | 0 | 0 | 0 | 8 | 3 | 3 | 5.93 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 46 | 0 | 5 | 1 | 4.33 | .304 | 1.28 | 7.4 | 4.2 | 10.2 | 60.1 | 49 | 29 | 29 | 8 | 28 | 68 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.97 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 44 | 43 | 0 | 1 | 2 | 4.44 | .318 | 1.36 | 7.7 | 4.7 | 9.5 | 50.2 | 43 | 27 | 25 | 8 | 26 | 53 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.64 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 34 | 49 | 0 | 2 | 2 | 3.15 | .294 | 1.17 | 6.5 | 4.1 | 8.9 | 60.0 | 43 | 22 | 21 | 6 | 27 | 59 | 0 | 10 | 0 | 0 | 0 | 5 | 3 | 3.93 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 23 | 33 | 0 | 0 | 1 | 5.08 | .392 | 1.93 | 11.7 | 6.0 | 10.6 | 33.2 | 43 | 22 | 19 | 7 | 22 | 39 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 5.39 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 3 | 1 | 0 | 1 | 6.14 | .333 | 1.36 | 7.7 | 5.1 | 5.1 | 7.1 | 6 | 5 | 5 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.00 |
| SP | Volquez, E.Volquez, Edinson >> | 25 | 2008 | R | 25 | 18 | 0 | 3 | 3 | 6.33 | .337 | 1.52 | 9.4 | 4.5 | 9.0 | 42.2 | 44 | 30 | 30 | 8 | 21 | 42 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 4.98 |