| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 34 | 34 | 12 | 15 | 4.21 | .284 | 1.15 | 8.1 | 2.4 | 9.7 | 256.2 | 229 | 121 | 120 | 34 | 67 | 275 | 7 | 0 | 0 | 2 | 15 | 10 | 4 | 3.48 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 33 | 33 | 11 | 15 | 5.80 | .338 | 1.52 | 10.6 | 3.1 | 7.3 | 180.0 | 211 | 122 | 116 | 47 | 62 | 146 | 2 | 0 | 0 | 0 | 14 | 3 | 3 | 5.86 |
| SP | Duchscherer, J.Duchscherer, Justin # >> | 31 | 2008 | R | 85 | 31 | 31 | 16 | 6 | 3.29 | .289 | 1.18 | 7.7 | 2.9 | 6.3 | 200.0 | 172 | 80 | 73 | 19 | 64 | 141 | 0 | 0 | 0 | 0 | 23 | 8 | 3 | 3.91 |
| CL | Putz, J.Putz, J.J. † $ >> | 30 | 2007 | R | 99 | 57 | 0 | 1 | 6 | 3.99 | .264 | 1.02 | 6.4 | 2.9 | 8.1 | 58.2 | 41 | 26 | 26 | 4 | 19 | 52 | 0 | 36 | 2 | 0 | 0 | 3 | 0 | 3.24 |
| SU | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 86 | 61 | 0 | 2 | 0 | 4.78 | .310 | 1.35 | 9.3 | 3.0 | 9.1 | 69.2 | 71 | 37 | 37 | 13 | 23 | 70 | 0 | 2 | 6 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 50 | 0 | 2 | 0 | 5.89 | .311 | 1.31 | 7.7 | 4.2 | 7.7 | 47.1 | 40 | 33 | 31 | 7 | 22 | 40 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 4.77 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 41 | 0 | 3 | 2 | 4.06 | .298 | 1.27 | 7.5 | 4.1 | 10.9 | 37.2 | 31 | 21 | 17 | 3 | 17 | 45 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 54 | 71 | 0 | 6 | 3 | 4.50 | .318 | 1.36 | 8.6 | 3.6 | 9.4 | 50.0 | 48 | 28 | 25 | 9 | 20 | 52 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.58 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 52 | 29 | 0 | 3 | 1 | 4.71 | .323 | 1.36 | 9.3 | 3.0 | 6.8 | 114.2 | 118 | 65 | 60 | 19 | 38 | 86 | 0 | 0 | 0 | 0 | 0 | 8 | 4 | 4.87 |