| SP | Clemens, R.Clemens, Roger † >> | 43 | 2005 | R | 94 | 33 | 33 | 12 | 10 | 4.56 | .326 | 1.43 | 9.3 | 3.5 | 8.0 | 213.1 | 220 | 116 | 108 | 28 | 84 | 190 | 2 | 0 | 0 | 1 | 14 | 6 | 2 | 4.19 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 32 | 32 | 8 | 10 | 5.73 | .352 | 1.59 | 11.1 | 3.1 | 6.9 | 143.0 | 177 | 97 | 91 | 17 | 50 | 109 | 0 | 0 | 0 | 0 | 2 | 6 | 3 | 4.20 |
| SP | Oswalt, R.Oswalt, Roy # >> | 24 | 2001 | R | 71 | 32 | 32 | 8 | 8 | 5.14 | .327 | 1.43 | 10.5 | 2.4 | 8.4 | 161.0 | 188 | 97 | 92 | 27 | 43 | 150 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 4.19 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 65 | 32 | 32 | 12 | 10 | 5.25 | .341 | 1.52 | 10.8 | 2.9 | 6.4 | 202.1 | 243 | 127 | 118 | 31 | 64 | 143 | 3 | 0 | 0 | 1 | 13 | 7 | 4 | 4.63 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 75 | 31 | 31 | 12 | 10 | 4.87 | .332 | 1.46 | 9.4 | 3.7 | 8.8 | 188.1 | 197 | 105 | 102 | 28 | 78 | 184 | 0 | 0 | 0 | 0 | 13 | 6 | 2 | 4.32 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 74 | 0 | 6 | 6 | 3.58 | .282 | 1.17 | 6.9 | 3.6 | 5.6 | 83.0 | 64 | 34 | 33 | 8 | 33 | 52 | 0 | 27 | 4 | 0 | 0 | 1 | 0 | 4.23 |
| SU | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 86 | 0 | 4 | 3 | 3.96 | .301 | 1.25 | 9.0 | 2.3 | 10.2 | 97.2 | 97 | 50 | 43 | 11 | 25 | 110 | 0 | 3 | 4 | 0 | 0 | 4 | 8 | 3.10 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 66 | 91 | 0 | 2 | 0 | 3.66 | .322 | 1.38 | 7.7 | 4.7 | 7.9 | 96.0 | 82 | 45 | 39 | 12 | 50 | 84 | 0 | 2 | 4 | 0 | 0 | 5 | 3 | 4.59 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 34 | 0 | 7 | 7 | 5.53 | .331 | 1.43 | 9.0 | 3.9 | 9.0 | 55.1 | 55 | 36 | 34 | 14 | 24 | 55 | 0 | 6 | 1 | 0 | 0 | 3 | 1 | 5.78 |