| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 37 | 37 | 14 | 8 | 3.03 | .284 | 1.17 | 7.4 | 3.1 | 8.9 | 249.2 | 204 | 86 | 84 | 22 | 87 | 245 | 0 | 0 | 0 | 0 | 29 | 6 | 4 | 3.30 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 37 | 37 | 14 | 12 | 4.03 | .293 | 1.22 | 8.7 | 2.3 | 5.9 | 241.0 | 233 | 116 | 108 | 26 | 61 | 158 | 8 | 0 | 0 | 1 | 21 | 6 | 2 | 3.93 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 34 | 34 | 16 | 13 | 3.61 | .295 | 1.23 | 6.4 | 4.7 | 7.2 | 214.1 | 151 | 91 | 86 | 19 | 112 | 172 | 2 | 0 | 0 | 1 | 25 | 6 | 5 | 4.20 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 34 | 34 | 18 | 7 | 2.90 | .283 | 1.16 | 7.2 | 3.3 | 3.9 | 254.2 | 202 | 88 | 82 | 19 | 94 | 110 | 6 | 0 | 0 | 1 | 26 | 5 | 1 | 4.28 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 65 | 0 | 6 | 5 | 2.66 | .262 | 1.02 | 5.9 | 3.4 | 7.8 | 67.2 | 44 | 22 | 20 | 8 | 25 | 58 | 0 | 31 | 3 | 0 | 0 | 3 | 3 | 4.07 |
| RP | Benitez, A.Benitez, Armando # >> | 32 | 2004 | R | 82 | 51 | 0 | 3 | 2 | 5.49 | .298 | 1.27 | 8.5 | 3.0 | 4.6 | 57.1 | 54 | 40 | 35 | 11 | 19 | 29 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 5.49 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 38 | 0 | 3 | 3 | 4.14 | .294 | 1.23 | 8.8 | 2.4 | 6.2 | 45.2 | 44 | 21 | 21 | 8 | 12 | 31 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 4.80 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 35 | 0 | 1 | 1 | 4.43 | .289 | 1.20 | 7.7 | 3.2 | 9.2 | 42.2 | 36 | 21 | 21 | 7 | 15 | 43 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.26 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 7 | 2 | 2 | 2 | 3.04 | .252 | 1.01 | 5.5 | 3.8 | 8.0 | 26.2 | 16 | 13 | 9 | 4 | 11 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.50 |