| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 22 | 22 | 8 | 10 | 4.29 | .285 | 1.18 | 8.3 | 2.3 | 4.6 | 161.2 | 148 | 95 | 77 | 16 | 42 | 82 | 8 | 0 | 0 | 1 | 12 | 3 | 1 | 4.11 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 21 | 21 | 5 | 11 | 6.52 | .351 | 1.59 | 10.9 | 3.4 | 8.3 | 116.0 | 141 | 91 | 84 | 27 | 44 | 107 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 5.40 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 20 | 20 | 6 | 9 | 4.66 | .307 | 1.30 | 9.5 | 2.2 | 7.8 | 133.1 | 140 | 78 | 69 | 22 | 33 | 116 | 1 | 0 | 0 | 0 | 8 | 4 | 1 | 4.24 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 20 | 20 | 5 | 9 | 4.23 | .317 | 1.37 | 9.1 | 3.3 | 3.4 | 125.2 | 126 | 64 | 59 | 19 | 46 | 47 | 1 | 0 | 0 | 1 | 9 | 3 | 1 | 5.40 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 54 | 0 | 2 | 2 | 3.89 | .309 | 1.31 | 7.6 | 4.3 | 9.6 | 71.2 | 60 | 32 | 31 | 10 | 34 | 76 | 0 | 5 | 1 | 0 | 0 | 2 | 3 | 4.21 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 44 | 0 | 6 | 4 | 4.78 | .335 | 1.49 | 8.2 | 5.3 | 7.0 | 58.1 | 53 | 33 | 31 | 12 | 34 | 45 | 0 | 4 | 3 | 0 | 0 | 1 | 2 | 5.95 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 39 | 0 | 3 | 3 | 5.57 | .337 | 1.48 | 8.1 | 5.1 | 11.1 | 42.0 | 38 | 28 | 26 | 10 | 24 | 52 | 0 | 5 | 1 | 0 | 0 | 2 | 2 | 5.48 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |