| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 34 | 34 | 16 | 13 | 3.75 | .281 | 1.13 | 7.8 | 2.4 | 8.6 | 249.2 | 216 | 110 | 104 | 26 | 66 | 238 | 3 | 0 | 0 | 1 | 23 | 11 | 5 | 3.37 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 30 | 30 | 6 | 19 | 6.98 | .374 | 1.77 | 11.8 | 4.1 | 5.7 | 184.1 | 242 | 149 | 143 | 22 | 84 | 117 | 6 | 0 | 0 | 0 | 7 | 5 | 11 | 4.73 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 85 | 0 | 6 | 8 | 3.81 | .299 | 1.27 | 7.4 | 4.1 | 9.2 | 115.2 | 95 | 55 | 49 | 11 | 52 | 117 | 0 | 2 | 6 | 0 | 0 | 1 | 2 | 3.59 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 73 | 0 | 4 | 5 | 4.48 | .313 | 1.37 | 8.5 | 3.9 | 7.4 | 86.1 | 81 | 47 | 43 | 16 | 37 | 71 | 0 | 10 | 2 | 0 | 0 | 0 | 1 | 5.06 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 53 | 0 | 6 | 2 | 2.73 | .264 | 1.05 | 7.5 | 1.9 | 6.7 | 66.0 | 55 | 21 | 20 | 7 | 14 | 49 | 0 | 3 | 2 | 0 | 0 | 2 | 2 | 3.62 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 19 | 1 | 2 | 1 | 8.17 | .411 | 2.09 | 15.5 | 3.6 | 7.6 | 25.1 | 43 | 23 | 23 | 6 | 10 | 21 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.64 |