| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 20 | 20 | 9 | 5 | 3.78 | .279 | 1.15 | 7.4 | 2.9 | 8.1 | 143.0 | 118 | 62 | 60 | 19 | 46 | 129 | 2 | 0 | 0 | 0 | 13 | 2 | 1 | 3.93 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 19 | 19 | 12 | 3 | 3.25 | .280 | 1.14 | 8.4 | 1.9 | 5.3 | 146.2 | 136 | 58 | 53 | 16 | 31 | 86 | 3 | 0 | 0 | 1 | 12 | 4 | 8 | 3.97 |
| SP | Johnson, W.Johnson, Walter # >> | 26 | 1913 | R | 95 | 19 | 19 | 9 | 6 | 4.63 | .292 | 1.22 | 8.9 | 2.1 | 5.5 | 134.0 | 132 | 73 | 69 | 14 | 32 | 82 | 2 | 0 | 0 | 1 | 8 | 2 | 5 | 3.90 |
| SP | Lundgren, C.Lundgren, Carl # >> | 27 | 1907 | R | 43 | 18 | 18 | 10 | 3 | 5.23 | .355 | 1.62 | 8.7 | 6.0 | 4.0 | 113.2 | 109 | 75 | 66 | 11 | 75 | 50 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 5.48 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 44 | 0 | 2 | 5 | 3.35 | .292 | 1.19 | 7.0 | 3.8 | 9.7 | 40.1 | 31 | 15 | 15 | 2 | 17 | 43 | 0 | 31 | 1 | 0 | 0 | 2 | 0 | 2.93 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 28 | 0 | 5 | 0 | 3.26 | .283 | 1.19 | 9.3 | 1.5 | 7.8 | 30.1 | 31 | 11 | 11 | 5 | 5 | 26 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 3.93 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 18 | 0 | 3 | 3 | 4.80 | .328 | 1.47 | 8.4 | 4.8 | 7.8 | 15.0 | 14 | 9 | 8 | 3 | 8 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.47 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 9 | 0 | 0 | 0 | 3.38 | .351 | 1.63 | 11.3 | 3.4 | 9.0 | 8.0 | 10 | 3 | 3 | 1 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 17 | 15 | 3 | 8 | 5.84 | .330 | 1.48 | 9.3 | 4.0 | 4.7 | 103.1 | 107 | 73 | 67 | 16 | 46 | 54 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 5.31 |