| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 34 | 34 | 12 | 17 | 4.24 | .297 | 1.25 | 9.0 | 2.3 | 4.5 | 256.2 | 256 | 123 | 121 | 28 | 65 | 128 | 10 | 0 | 0 | 2 | 16 | 5 | 6 | 4.24 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 33 | 33 | 8 | 14 | 5.17 | .317 | 1.37 | 9.6 | 2.7 | 7.8 | 233.1 | 249 | 134 | 134 | 28 | 70 | 201 | 3 | 0 | 0 | 1 | 12 | 6 | 5 | 3.82 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 29 | 29 | 14 | 6 | 4.47 | .326 | 1.44 | 8.1 | 4.9 | 8.5 | 173.0 | 155 | 90 | 86 | 32 | 94 | 164 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 5.17 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 93 | 0 | 9 | 9 | 3.48 | .277 | 1.14 | 7.6 | 2.8 | 10.3 | 121.2 | 102 | 52 | 47 | 20 | 37 | 139 | 0 | 9 | 7 | 0 | 0 | 1 | 0 | 3.79 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 83 | 0 | 10 | 6 | 2.48 | .241 | 0.94 | 6.6 | 2.0 | 8.1 | 101.2 | 74 | 30 | 28 | 8 | 22 | 91 | 0 | 11 | 3 | 0 | 0 | 1 | 2 | 2.91 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 48 | 0 | 2 | 7 | 4.63 | .332 | 1.47 | 9.6 | 3.7 | 5.6 | 58.1 | 62 | 30 | 30 | 8 | 24 | 36 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 4.84 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 29 | 0 | 2 | 2 | 4.93 | .324 | 1.38 | 7.8 | 4.7 | 6.9 | 38.1 | 33 | 24 | 21 | 4 | 20 | 29 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.58 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 8 | 2 | 2 | 2 | 5.23 | .347 | 1.50 | 11.3 | 2.7 | 5.0 | 20.2 | 25 | 13 | 12 | 4 | 6 | 11 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 5.70 |