| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 22 | 22 | 10 | 9 | 4.54 | .280 | 1.16 | 8.3 | 2.2 | 7.9 | 144.2 | 133 | 75 | 73 | 21 | 35 | 127 | 4 | 0 | 0 | 1 | 11 | 1 | 0 | 3.88 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 21 | 21 | 8 | 9 | 4.47 | .317 | 1.39 | 9.8 | 2.7 | 5.2 | 147.0 | 160 | 80 | 73 | 13 | 44 | 85 | 6 | 0 | 0 | 1 | 9 | 1 | 1 | 3.91 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 21 | 21 | 6 | 7 | 4.61 | .321 | 1.34 | 9.9 | 2.2 | 5.4 | 107.1 | 118 | 65 | 55 | 11 | 26 | 64 | 0 | 0 | 0 | 0 | 5 | 8 | 2 | 4.09 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 21 | 20 | 2 | 12 | 5.47 | .355 | 1.63 | 11.3 | 3.4 | 5.3 | 133.1 | 167 | 92 | 81 | 22 | 50 | 79 | 4 | 0 | 0 | 1 | 7 | 3 | 1 | 5.16 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 59 | 0 | 2 | 1 | 3.91 | .330 | 1.48 | 6.5 | 6.8 | 11.9 | 46.0 | 33 | 21 | 20 | 2 | 35 | 61 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.20 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 54 | 0 | 2 | 2 | 5.40 | .354 | 1.65 | 10.7 | 4.2 | 8.1 | 58.1 | 69 | 37 | 35 | 8 | 27 | 52 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.40 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 45 | 0 | 2 | 4 | 3.83 | .277 | 1.15 | 8.0 | 2.3 | 9.7 | 54.0 | 48 | 25 | 23 | 10 | 14 | 58 | 0 | 3 | 2 | 0 | 0 | 0 | 3 | 4.04 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 32 | 0 | 2 | 0 | 5.92 | .309 | 1.34 | 7.8 | 4.3 | 6.2 | 38.0 | 33 | 25 | 25 | 6 | 18 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.11 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 34 | 0 | 2 | 5 | 5.49 | .328 | 1.44 | 9.0 | 4.0 | 10.3 | 41.0 | 41 | 28 | 25 | 8 | 18 | 47 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.63 |