| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 25 | 25 | 9 | 10 | 3.99 | .299 | 1.28 | 8.1 | 3.4 | 8.1 | 162.1 | 145 | 77 | 72 | 22 | 62 | 146 | 3 | 0 | 0 | 2 | 14 | 1 | 3 | 4.13 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 24 | 24 | 8 | 10 | 5.60 | .358 | 1.65 | 10.8 | 4.1 | 7.9 | 146.1 | 175 | 102 | 91 | 22 | 67 | 128 | 1 | 0 | 0 | 0 | 11 | 3 | 0 | 4.64 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 24 | 24 | 7 | 11 | 4.78 | .340 | 1.53 | 10.2 | 3.6 | 4.1 | 156.1 | 177 | 88 | 83 | 15 | 62 | 71 | 2 | 0 | 0 | 0 | 13 | 3 | 7 | 4.59 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 24 | 24 | 8 | 8 | 5.13 | .341 | 1.55 | 10.2 | 3.7 | 3.2 | 140.1 | 159 | 84 | 80 | 17 | 58 | 50 | 1 | 0 | 0 | 0 | 10 | 1 | 4 | 5.13 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 63 | 0 | 8 | 2 | 3.05 | .274 | 1.12 | 7.8 | 2.4 | 9.0 | 94.1 | 81 | 36 | 32 | 7 | 25 | 94 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 2.80 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 62 | 0 | 4 | 3 | 3.35 | .311 | 1.34 | 8.0 | 4.2 | 7.8 | 80.2 | 71 | 33 | 30 | 11 | 37 | 69 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 4.49 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 46 | 0 | 3 | 1 | 2.23 | .233 | 0.91 | 6.6 | 1.7 | 9.3 | 64.2 | 47 | 18 | 16 | 4 | 12 | 66 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 2.31 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 47 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |