| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 16 | 16 | 7 | 8 | 3.78 | .314 | 1.35 | 9.0 | 3.2 | 9.2 | 123.2 | 123 | 54 | 52 | 14 | 44 | 126 | 4 | 0 | 0 | 0 | 8 | 3 | 1 | 3.58 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 15 | 15 | 8 | 5 | 3.34 | .293 | 1.21 | 8.4 | 2.5 | 5.4 | 110.1 | 103 | 43 | 41 | 7 | 31 | 66 | 1 | 0 | 0 | 1 | 11 | 3 | 0 | 3.55 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 15 | 15 | 6 | 7 | 3.97 | .281 | 1.16 | 8.4 | 2.1 | 6.4 | 111.0 | 103 | 50 | 49 | 11 | 26 | 79 | 3 | 0 | 0 | 2 | 7 | 1 | 0 | 3.59 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 15 | 15 | 5 | 6 | 5.22 | .333 | 1.46 | 9.8 | 3.4 | 4.4 | 98.1 | 107 | 59 | 57 | 8 | 37 | 48 | 3 | 0 | 0 | 0 | 6 | 3 | 2 | 4.31 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 32 | 0 | 0 | 2 | 2.31 | .239 | 0.94 | 5.7 | 2.8 | 7.5 | 35.0 | 22 | 11 | 9 | 5 | 11 | 29 | 0 | 19 | 2 | 0 | 0 | 0 | 0 | 4.14 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 28 | 0 | 2 | 3 | 9.95 | .429 | 2.25 | 15.1 | 5.4 | 6.8 | 25.1 | 42 | 28 | 28 | 7 | 15 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.92 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 18 | 0 | 0 | 0 | 3.98 | .337 | 1.48 | 10.8 | 2.7 | 10.4 | 20.1 | 24 | 9 | 9 | 2 | 6 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.05 |