| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 24 | 24 | 13 | 8 | 2.95 | .278 | 1.11 | 6.7 | 3.3 | 9.1 | 164.2 | 122 | 59 | 54 | 11 | 61 | 165 | 2 | 0 | 0 | 0 | 19 | 7 | 7 | 3.10 |
| SP | Alexander, P.Alexander, Pete # >> | 28 | 1915 | R | 88 | 24 | 24 | 9 | 10 | 3.87 | .282 | 1.14 | 8.4 | 1.9 | 4.7 | 163.0 | 152 | 76 | 70 | 16 | 34 | 86 | 6 | 0 | 0 | 0 | 15 | 6 | 2 | 3.96 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 23 | 22 | 6 | 12 | 5.37 | .333 | 1.48 | 9.4 | 3.9 | 7.6 | 119.0 | 124 | 75 | 71 | 14 | 52 | 101 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 4.19 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 21 | 21 | 8 | 8 | 3.38 | .299 | 1.27 | 6.7 | 4.7 | 3.8 | 138.1 | 103 | 56 | 52 | 6 | 72 | 58 | 1 | 0 | 0 | 0 | 14 | 2 | 2 | 4.33 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 61 | 0 | 6 | 3 | 2.51 | .237 | 0.87 | 5.5 | 2.3 | 7.5 | 86.0 | 53 | 24 | 24 | 8 | 22 | 72 | 0 | 1 | 4 | 0 | 0 | 5 | 0 | 3.48 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 32 | 0 | 2 | 0 | 3.57 | .284 | 1.16 | 7.5 | 3.1 | 10.0 | 35.1 | 29 | 14 | 14 | 4 | 12 | 39 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 3.37 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 95 | 50 | 0 | 4 | 4 | 2.30 | .237 | 0.93 | 5.7 | 2.8 | 6.3 | 54.2 | 34 | 15 | 14 | 3 | 17 | 38 | 0 | 25 | 2 | 0 | 0 | 0 | 2 | 3.26 |