| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 26 | 26 | 8 | 16 | 4.64 | .330 | 1.44 | 9.5 | 3.5 | 4.1 | 176.1 | 186 | 101 | 91 | 21 | 68 | 80 | 4 | 0 | 0 | 1 | 11 | 6 | 6 | 4.90 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 25 | 25 | 7 | 13 | 4.79 | .331 | 1.47 | 9.4 | 3.9 | 5.8 | 163.1 | 170 | 92 | 87 | 18 | 70 | 105 | 2 | 0 | 0 | 2 | 12 | 2 | 0 | 4.47 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 70 | 25 | 25 | 8 | 15 | 5.05 | .328 | 1.45 | 10.0 | 3.1 | 7.8 | 162.1 | 180 | 95 | 91 | 28 | 56 | 140 | 1 | 0 | 0 | 0 | 10 | 2 | 4 | 4.59 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 62 | 24 | 24 | 9 | 10 | 3.43 | .300 | 1.27 | 8.4 | 3.1 | 4.3 | 147.0 | 137 | 62 | 56 | 12 | 50 | 71 | 1 | 0 | 0 | 1 | 13 | 2 | 2 | 4.16 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 73 | 0 | 0 | 1 | 3.55 | .274 | 1.13 | 7.9 | 2.3 | 10.4 | 58.1 | 51 | 24 | 23 | 7 | 15 | 67 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.03 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 76 | 0 | 0 | 0 | 2.71 | .252 | 1.00 | 6.9 | 2.1 | 9.2 | 76.1 | 58 | 25 | 23 | 6 | 18 | 78 | 0 | 10 | 3 | 0 | 0 | 1 | 0 | 2.72 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 52 | 0 | 3 | 7 | 5.05 | .292 | 1.22 | 7.4 | 3.6 | 8.7 | 62.1 | 51 | 36 | 35 | 5 | 25 | 60 | 0 | 6 | 2 | 0 | 0 | 1 | 1 | 3.37 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 36 | 0 | 3 | 0 | 2.79 | .272 | 1.12 | 7.1 | 3.0 | 8.6 | 42.0 | 33 | 15 | 13 | 4 | 14 | 40 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 8 | 0 | 0 | 0 | 5.14 | .382 | 1.86 | 11.6 | 5.1 | 2.6 | 7.0 | 9 | 4 | 4 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.14 |