| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 13 | 13 | 6 | 5 | 3.97 | .322 | 1.37 | 9.7 | 2.7 | 9.8 | 79.1 | 85 | 45 | 35 | 8 | 24 | 86 | 0 | 0 | 0 | 0 | 6 | 4 | 0 | 3.20 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 13 | 13 | 4 | 6 | 4.23 | .313 | 1.33 | 8.8 | 3.2 | 8.6 | 89.1 | 87 | 44 | 42 | 15 | 32 | 85 | 1 | 0 | 0 | 0 | 8 | 3 | 3 | 4.46 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 27 | 0 | 4 | 2 | 4.97 | .310 | 1.31 | 6.8 | 5.0 | 8.1 | 29.0 | 22 | 16 | 16 | 2 | 16 | 26 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 3.86 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 20 | 0 | 0 | 1 | 5.79 | .417 | 2.14 | 12.2 | 7.1 | 7.7 | 14.0 | 19 | 9 | 9 | 0 | 11 | 12 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 12 | 0 | 1 | 2 | 1.65 | .269 | 1.04 | 5.6 | 3.9 | 7.9 | 16.1 | 10 | 3 | 3 | 0 | 7 | 14 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.75 |