| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 21 | 21 | 6 | 11 | 5.24 | .301 | 1.26 | 8.5 | 2.9 | 8.4 | 125.1 | 118 | 75 | 73 | 19 | 40 | 117 | 2 | 0 | 0 | 0 | 11 | 4 | 4 | 4.16 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 20 | 20 | 5 | 14 | 5.56 | .305 | 1.30 | 8.8 | 2.9 | 8.9 | 126.1 | 123 | 84 | 78 | 28 | 41 | 125 | 1 | 0 | 0 | 0 | 7 | 2 | 3 | 4.93 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 19 | 19 | 6 | 6 | 6.01 | .334 | 1.50 | 10.1 | 3.4 | 6.3 | 106.1 | 119 | 78 | 71 | 24 | 40 | 74 | 1 | 0 | 0 | 0 | 6 | 1 | 4 | 5.71 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 46 | 0 | 5 | 5 | 4.69 | .311 | 1.31 | 9.4 | 2.4 | 7.1 | 48.0 | 50 | 26 | 25 | 9 | 13 | 38 | 0 | 21 | 5 | 0 | 0 | 2 | 3 | 4.79 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 50 | 0 | 5 | 1 | 3.93 | .298 | 1.22 | 7.2 | 3.8 | 11.5 | 55.0 | 44 | 25 | 24 | 8 | 23 | 70 | 0 | 1 | 2 | 0 | 0 | 3 | 4 | 3.76 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 32 | 0 | 0 | 0 | 6.58 | .304 | 1.26 | 8.8 | 2.8 | 8.3 | 39.2 | 38 | 30 | 29 | 14 | 12 | 36 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 6.90 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 32 | 0 | 1 | 3 | 3.96 | .318 | 1.40 | 8.8 | 4.0 | 9.2 | 38.2 | 37 | 22 | 17 | 8 | 17 | 39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.03 |