| SP | Arrieta, J.Arrieta, Jake † # >> | 29 | 2015 | R | 95 | 22 | 22 | 11 | 8 | 2.92 | .264 | 1.06 | 7.7 | 1.8 | 8.6 | 172.2 | 148 | 59 | 56 | 21 | 35 | 164 | 6 | 0 | 0 | 1 | 15 | 3 | 2 | 3.34 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 21 | 21 | 5 | 9 | 6.55 | .356 | 1.64 | 10.9 | 3.8 | 5.8 | 103.0 | 125 | 79 | 75 | 19 | 44 | 66 | 0 | 0 | 0 | 0 | 4 | 2 | 6 | 5.46 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 20 | 20 | 6 | 6 | 4.27 | .330 | 1.46 | 10.2 | 3.0 | 6.7 | 122.1 | 138 | 61 | 58 | 18 | 41 | 91 | 0 | 0 | 0 | 0 | 10 | 2 | 2 | 4.48 |
| SP | Smoltz, J.Smoltz, John >> | 29 | 1996 | R | 62 | 20 | 20 | 6 | 11 | 5.18 | .345 | 1.56 | 10.0 | 4.0 | 9.6 | 132.0 | 147 | 76 | 76 | 14 | 59 | 141 | 0 | 0 | 0 | 0 | 9 | 3 | 11 | 3.65 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 56 | 0 | 1 | 2 | 3.38 | .293 | 1.22 | 6.8 | 4.3 | 9.6 | 74.2 | 56 | 29 | 28 | 8 | 35 | 79 | 0 | 5 | 4 | 0 | 0 | 2 | 2 | 3.77 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 51 | 0 | 3 | 3 | 3.47 | .263 | 1.04 | 6.2 | 3.2 | 8.5 | 57.0 | 39 | 23 | 22 | 5 | 20 | 54 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.40 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 42 | 0 | 7 | 3 | 3.81 | .303 | 1.31 | 8.2 | 3.7 | 7.8 | 54.1 | 49 | 23 | 23 | 7 | 22 | 47 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 32 | 0 | 0 | 2 | 2.15 | .231 | 0.90 | 5.6 | 2.7 | 8.8 | 37.2 | 23 | 9 | 9 | 4 | 11 | 36 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 3.35 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 49 | 25 | 0 | 1 | 1 | 3.21 | .317 | 1.39 | 9.6 | 2.9 | 9.6 | 28.0 | 30 | 10 | 10 | 4 | 9 | 30 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.68 |