| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 29 | 28 | 6 | 6 | 5.06 | .333 | 1.49 | 9.3 | 4.2 | 8.2 | 156.2 | 161 | 91 | 88 | 32 | 72 | 142 | 0 | 0 | 0 | 0 | 11 | 2 | 12 | 5.27 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 67 | 29 | 28 | 8 | 9 | 6.55 | .354 | 1.62 | 10.5 | 4.1 | 9.4 | 136.0 | 158 | 103 | 99 | 21 | 62 | 142 | 0 | 0 | 0 | 0 | 10 | 4 | 3 | 4.38 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 27 | 27 | 13 | 7 | 4.36 | .316 | 1.38 | 8.1 | 4.2 | 6.4 | 157.0 | 142 | 80 | 76 | 14 | 74 | 111 | 1 | 0 | 0 | 0 | 14 | 2 | 4 | 4.20 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 28 | 26 | 5 | 15 | 5.03 | .331 | 1.47 | 10.0 | 3.3 | 8.7 | 171.2 | 190 | 99 | 96 | 27 | 63 | 165 | 2 | 0 | 0 | 0 | 12 | 2 | 3 | 4.26 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 74 | 0 | 2 | 5 | 4.99 | .322 | 1.39 | 10.3 | 2.3 | 8.6 | 95.2 | 109 | 53 | 53 | 9 | 24 | 91 | 0 | 6 | 4 | 0 | 0 | 3 | 0 | 3.17 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 55 | 0 | 7 | 5 | 3.64 | .320 | 1.41 | 9.1 | 3.7 | 8.6 | 64.1 | 65 | 30 | 26 | 5 | 26 | 61 | 0 | 3 | 4 | 0 | 0 | 0 | 4 | 3.33 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 39 | 0 | 5 | 0 | 1.80 | .278 | 1.13 | 5.8 | 4.4 | 7.4 | 45.0 | 29 | 9 | 9 | 0 | 22 | 37 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 2.89 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 29 | 0 | 1 | 2 | 2.83 | .276 | 1.09 | 7.5 | 2.3 | 8.0 | 35.0 | 29 | 11 | 11 | 6 | 9 | 31 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 4.40 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 24 | 0 | 2 | 1 | 3.55 | .283 | 1.18 | 7.2 | 3.6 | 9.0 | 25.1 | 20 | 10 | 10 | 2 | 10 | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.24 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 27 | 0 | 0 | 2 | 6.83 | .394 | 1.88 | 10.0 | 7.3 | 12.0 | 27.2 | 30 | 22 | 21 | 6 | 22 | 36 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.89 |